Evidence map›Paper›PMID 40369152›Full record

Trial reportAesthetic plastic surgery2025

Clinical Efficacy Analysis of Botulinum Toxin Type A Combined with Superficial Radiotherapy after Chest Keloid Surgery.

Ya Gao, Wenbo Li, Zhongxing Li, Fenglian Wu, Jiaxin Wang

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ya GaoDepartment of Graduate School, Hebei North University, Qiaoxi District, Zhangjiakou City, 075000, Hebei Province, China.
Wenbo LiDepartment of Plastic and Cosmetic Surgery, Department of Surgery, First Hospital of Qinhuangdao, No. 258, Wenhua Road, Haigang District, Qinhuangdao City, 066000, Hebei Province, China.
Zhongxing LiDepartment of Plastic and Cosmetic Surgery, Department of Surgery, First Hospital of Qinhuangdao, No. 258, Wenhua Road, Haigang District, Qinhuangdao City, 066000, Hebei Province, China.
Fenglian WuDepartment of Plastic and Cosmetic Surgery, Department of Surgery, First Hospital of Qinhuangdao, No. 258, Wenhua Road, Haigang District, Qinhuangdao City, 066000, Hebei Province, China.
Jiaxin WangDepartment of Plastic and Cosmetic Surgery, Department of Surgery, First Hospital of Qinhuangdao, No. 258, Wenhua Road, Haigang District, Qinhuangdao City, 066000, Hebei Province, China. 878648593@qq.com.ORCID 0009-0004-6084-2506

Funding

Health Commission of Hebei Province 20231886
6 · The paper itself

Abstract

backgroundThere are many treatments for keloid. In recent years, botulinum toxin type A(BTX-A)has been proposed to treat keloid. The purpose of our study was to observe the clinical effect of BTX-A combined with superficial radiotherapy after chest keloid surgery.

methods60 patients with medium and large chest keloid treated from October 2021 to October 2023 were selected and randomly divided into group A and group B, with 30 cases in each group. Keloid resection was performed in both groups first, group A was treated with BTX-A combined with superficial radiotherapy, group B only received early superficial radiotherapy after surgery, and the therapeutic effect of the two groups was compared.

resultsAfter 6 months follow-up observation, the total effective rate and satisfaction of group A were higher than those of group B, and the Vancouver scar scale(VSS) score of group A was lower than that of group B, the difference was statistically significant (P < 0.05).

conclusionsWe concluded that immediate injection of BTX-A combined with superficial radiotherapy after chest keloid surgery was superior to simple superficial radiotherapy after surgery, with higher patient satisfaction and lower recurrence rate, which was worthy of clinical application. LEVEL OF EVIDENCE II: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Botulinum Toxins, Type AKeloidNeuromuscular AgentsAdultCombined Modality TherapyFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionRadiotherapy, AdjuvantTreatment OutcomeYoung AdultBotulinum Toxins, Type ANeuromuscular AgentsBotulinum toxin type AChest keloidEfficacy analysisSuperficial radiotherapy

Identifiers

PMID40369152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.