Evidence map›Paper›PMID 40369084›Full record

ArticleNature2025

Divergent DNA methylation dynamics in marsupial and eutherian embryos.

Bryony J Leeke, Wazeer Varsally, Sugako Ogushi, Jasmin Zohren, Sergio Menchero, Aurélien Courtois, Daniel M Snell, Aurélie Teissandier, Obah Ojarikre, Shantha K Mahadevaiah and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bryony J Leeke *Sex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK. b.leeke@lms.mrc.ac.uk.ORCID 0000-0002-5572-8942
Wazeer Varsally *Sex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-4988-4551
Sugako OgushiSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0001-8497-6972
Jasmin ZohrenSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.
Sergio MencheroSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0003-4592-7259
Aurélien CourtoisSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0001-5988-8794
Daniel M SnellSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.ORCID 0000-0002-0105-8437
Aurélie TeissandierINSERM U934, CNRS UMR3215, Institut Curie, PSL Research University, Paris, France.
Obah OjarikreSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.
Shantha K MahadevaiahSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK.
Fanny DecarpentrieComparative Medicine, Novartis, Basel, Switzerland.
Rebecca J OakeyDepartment of Medical and Molecular Genetics, King's College London, London, UK.ORCID 0000-0003-2706-8139
John L VandeBergDivision of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, The University of Texas Rio Grande Valley, Brownsville, TX, USA.
James M A TurnerSex Chromosome Biology Laboratory, The Francis Crick Institute, London, UK. james.turner@crick.ac.uk.ORCID 0000-0003-1722-7677

Funding

Construction of a Biomedical Research Facility at the U*C06RR020547 · NCRR · UNIV/TEXAS BROWNSVILLE & SOUTHMOST COLL · PI KROUSE, JOHN H · 2010 to 2010
$4.0M
NCRR NIH HHS C06 RR020547Wellcome Trust FC001193
6 · The paper itself

Abstract

Based on seminal work in placental species (eutherians)

Indexed as

DNA MethylationEmbryo, MammalianEutheriaMonodelphisAnimalsBlastocystEmbryonic DevelopmentFemaleGenomic ImprintingGerm LayersMaleMarsupialiaOocytesPlacentaRNA, Long NoncodingSpermatozoaRNA, Long NoncodingXIST non-coding RNA

Identifiers

PMID40369084
PMCPMC12221971

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.