Evidence map›Paper›PMID 40369067›Full record

ArticleNature2025

Dopaminergic action prediction errors serve as a value-free teaching signal.

Francesca Greenstreet, Hernando Martinez Vergara, Yvonne Johansson, Sthitapranjya Pati, Laura Schwarz, Stephen C Lenzi, Jesse P Geerts, Matthew Wisdom, Alina Gubanova, Lars B Rollik and 7 more

Abstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
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  8. Chronic ethanol self-administration alters dopamine in the caudate nucleus and putamen of rhesus macaques in a sex-dependent manner.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Spatiotemporally Distinct Dopamine Domains in the Hippocampus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Mesocorticostriatal Reinforcement Learning of State Representation and Value with Implications for the Mechanisms of Schizophrenia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Francesca Greenstreet *Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0002-4847-8340
Hernando Martinez Vergara *Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0001-6904-2311
Yvonne Johansson *Sainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Sthitapranjya PatiSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Laura SchwarzSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Stephen C LenziSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Jesse P GeertsSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0003-2960-5727
Matthew WisdomSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Alina GubanovaSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Lars B RollikSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0003-0160-6971
Jasvin KaurSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Theodore MoskovitzGatsby Computational Neuroscience Unit, University College London, London, UK.
Joseph CohenSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Emmett ThompsonSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0001-5374-4407
Troy W MargrieSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.
Claudia ClopathSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK.ORCID 0000-0003-4507-8648
Marcus Stephenson-JonesSainsbury Wellcome Centre for Neural Circuits and Behaviour, University College London, London, UK. m.stephenson-jones@ucl.ac.uk.ORCID 0000-0003-4718-4452

Funding

Wellcome Trust
6 · The paper itself

Abstract

Choice behaviour of animals is characterized by two main tendencies: taking actions that led to rewards and repeating past actions

Indexed as

Choice BehaviorDopamineDopaminergic NeuronsReinforcement, PsychologyRewardAcoustic StimulationAnimalsComputer SimulationCorpus StriatumFemaleLearningMaleMiceMice, Inbred C57BLModels, NeurologicalMovementDopamine

Identifiers

PMID40369067
PMCPMC12310545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.