ArticleScientific reports2025
Gabapentin drug interactions in water and aqueous solutions of green betaine based compounds through volumetric, viscometric and interfacial properties.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Effects of some surface active ionic liquids on the aqueous solubility, thermodynamic properties and fluorescence behavior of drug diclofenac sodium.Scientific reports · 2026Article
- Enhancement of SiODiscover nano · 2026Article
- Current Status and Future Perspectives of Betaine and Betaine-Based Natural Deep Eutectic Solvents: A Review.Foods (Basel, Switzerland) · 2025Review
- The surface and micellar properties of ethanolamine based surface active ionic liquids in the presence of drug aspirin.Scientific reports · 2025Article
- Effect of 2-hydroxyethylammonium acetate based protic ionic liquids on thermophysical properties and taste behavior of D-fructose in aqueous solutions at different temperatures.Scientific reports · 2025Article
- The role of choline-based ionic liquids in modulating the thermophysical properties of d-fructose solutions.BMC chemistry · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Betaine as a bio-based surfactant, has been found in a variety of natural sources. Betaine improves drug absorption, protect drugs from degradation, and enhance the performance of various therapeutic and hygiene products. To investigate the interactions between gabapentin (an antiepileptic drug) and betaine-based compounds, series of experiments were conducted at 298 K. These experiments involved volumetric, viscometric, and surface tension measurements of aqueous solutions containing gabapentin and various betaine-based compounds, including betaine, betaine octyl ester chloride ionic liquid and betaine-urea deep eutectic solvent (molar ratio of 1:2). Additionally, the Conductor like Screening Model (COSMO) method were employed to gain further insights into molecular interactions governing these systems. The volumetric studies revealed that the standard partial molar volumes V
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Registered trials
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