ReviewBritish journal of haematology2025
The role of blinatumomab in adult acute B lymphoblastic leukaemia.
Review in British journal of haematology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Targeting drug efflux and DNA repair enhances inotuzumab ozogamicin activity in IO-resistant B-ALL cell lines.International journal of hematology · 2026Article
- A genomic and epigenomic lens into the biology of acute lymphoblastic leukaemia.Nature reviews. Cancer · 2026Review
- Breaching the Blood-Brain Barrier: Evolving Strategies for Central Nervous System Disease in Adult Acute Lymphoblastic Leukemia.Current hematologic malignancy reports · 2026Review
- The clinical characteristics and prognosis analysis of acute B-cell lymphoblastic leukemia with MEF2D fusions.Annals of hematology · 2026Article
- Commentary: Case Report: CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation triggers Purtscher-like retinopathy: clinical features and complement-mediated microvascular injury mechanisms.Frontiers in immunology · 2026Article
- The role of blinatumomab in adult acute B lymphoblastic leukaemia.British journal of haematology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blinatumomab is a CD19 × CD3-directed bispecific T-cell engager that has become an essential backbone of acute B lymphoblastic leukaemia (BCP-ALL) treatment. It is used in relapsed/refractory disease, minimal residual disease (MRD), as well as in first-line treatment. Blinatumomab is particularly effective in MRD-positive BCP-ALL, inducing a high rate of deep molecular response, with very good overall tolerability. Very promising data are reported for the addition of blinatumomab to first-line therapy. This review focusses on new aspects of blinatumomab treatment in Philadelphia-negative BCP-ALL treatment in adult patients, including MRD-positive and relapsed/refractory disease, as well as reviewing recent clinical trials implementing blinatumomab into first-line therapy of BCP-ALL treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.