Evidence map›Paper›PMID 40368641›Full record

ArticleCell proliferation2025

Nano-Mediated Fluorescence Switching for Epidermal Growth Factor Receptor Detection.

Xin Fu, Yuhao Wang, Wenxin Zhang, Yuepeng Yang, Jialin Zeng, Xiaodie Li, Chengyu Feng, Bin Li, Yingying Liu, Yinan Zhang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell proliferation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xin FuDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yuhao WangDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Wenxin ZhangDepartment of Pediatric Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Yuepeng YangDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Jialin ZengDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Xiaodie LiDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Chengyu FengDepartment of Pediatric Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.
Bin LiSchool of Inspection, Ningxia Medical University, Yinchuan, China.
Yingying LiuSchool of Chemistry and Chemical Engineering, Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine (Shanghai), Shanghai Jiao Tong University, Shanghai, China.
Yinan ZhangSchool of Chemical Science and Engineering, Tongji University, Shanghai, China.
Chao ZhangDepartment of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.ORCID https://orcid.org/0009-0007-8405-2164
Sicong MaDepartment of Intensive Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

Funding

Fundamental Research Funds for the Central Universities 22120230236Guangdong Basic and Applied Basic Research Foundation 2022A1515110845Guangdong Basic and Applied Basic Research Foundation 2023A1515011042National Natural Science Foundation of China 22207072National Natural Science Foundation of China 22207085National Natural Science Foundation of China 22304072National Natural Science Foundation of China 82373393Open competition mechanism to select the best candidates for key research projects of Ningxia Medical University XJKF230112President Foundation of ZhuJiang Hospital, Southern Medical University yzjj2023qn28
6 · The paper itself

Abstract

Identification of the epidermal growth factor receptor (EGFR) in biological specimens is essential for cancer diagnostics, drug development and therapeutic monitoring. However, real-time techniques for accurate EGFR expression monitoring are currently limited. In this study, we report the development of a novel nano detector (Cy3-Apt

Indexed as

ErbB ReceptorsNanostructuresAptamers, NucleotideBiosensing TechniquesCarbocyaninesCell Line, TumorFluorescenceFluorescent DyesHumansPhosphorusAptamers, NucleotideCarbocyaninescyanine dye 3EGFR protein, humanErbB ReceptorsFluorescent DyesPhosphorusaptamerblack phosphorus nanosheets (BPNSs)cancer diagnosticsepidermal growth factor receptor (EGFR)

Identifiers

PMID40368641
PMCPMC12686125

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.