ArticleEnvironmental research2025
Joint effects of environmental and neighborhood socioeconomic factors on cognitive function in the Heinz Nixdorf Recall Study.
Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Dietary Choline and Betaine Intake and 2-year Changes in Cognitive Function in Older Adults With Overweight or Obesity and Metabolic Syndrome: A Prospective Cohort Analysis.The American journal of clinical nutrition · 2026Article
- Association of Air Pollution and Socioeconomic Deprivation with Depression and Pain.International journal of environmental research and public health · 2026Article
- Associations between joint air pollution exposure, mental health, and physical health and dementia incidence in an aging U.S. cohort.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026Article
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10 authors.
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Abstract
backgroundModifiable physical and social environments are believed to influence cognitive health in older age.
objectivesTo employ cutting-edge methods to analyze the impact of correlated environmental and socioeconomic neighborhood factors on cognitive function in German older participants.
methodsIn the German Heinz Nixdorf Recall cohort study, participants underwent neuropsychological testing at the first follow-up examination (2006-2008) to derive a global cognitive score (GCS). Long-term exposure to air pollution was estimated by the land-use regression and chemistry transport models. Road traffic noise was assessed as outdoor weighted 24h and nighttime means. Seven neighborhood-level socioeconomic position (nSEP) characteristics were linked from administrative data. The joint effects of exposure combinations on GCS were estimated using two dimensionality reduction techniques: principal component (PC) analysis (PCA) and self-organizing maps (SOM).
resultsOverall, 3748 individuals were included (median age 65 years; 50.7 % female). In single-exposure linear regression analysis, higher particle matter with aerodynamic diameter ≤2.5 μm (PM DISCUSSION: We identified associations between distinct combinations of intercorrelated air pollution, road traffic noise, and nSEP disadvantages with poorer cognitive function, using two different dimensionality reduction methods. Our findings highlight the importance of considering combined environmental and social exposures to systematically assess the potential benefits of multimodal urban interventions aimed at mitigating these risk factors.
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