Evidence map›Paper›PMID 40367967›Full record

ArticleJournal of neural engineering2025

Closed-loop electrical block of vagus nerve scales from rodent to porcine cardiac models.

Shane Bender, David Green, Joseph Hadaya, Sahil Haridas, Christopher Chan, Ronald Challita, Al-Hassan Dajani, Jeffery Ardell, Tina Vrabec

Abstract read
In one paragraph

Article in Journal of neural engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Single-Electrode, Bidirectional Control of Heart Rate via Vagus Nerve Modulation in Rat Model.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shane BenderDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.ORCID 0000-0002-6197-8809
David GreenDepartment of Physical Medicine and Rehabilitation, MetroHealth Medical Center, Cleveland, OH, United States of America.ORCID 0000-0002-0025-3847
Joseph HadayaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0001-9902-0578
Sahil HaridasUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0009-0009-4922-1203
Christopher ChanUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.ORCID 0000-0002-0129-8473
Ronald ChallitaUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.
Al-Hassan DajaniUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.
Jeffery ArdellUCLA Cardiac Arrhythmia Center and Neurocardiology Research Program of Excellence, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States of America.
Tina VrabecDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.ORCID 0000-0003-1107-6409

Funding

Sterilization of the COSMIIC SystemU41NS129436 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI FU, MICHAEL JOHN, KILGORE, KEVIN L. · 2022 to 2024
$14.8M
Neural Control of Myocardial Excitability at the Nerve Myocyte InterfaceP01HL164311 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Olujimi A Ajijola · 2023 to 2026
$11.3M
Bioelectric monitoring and neuromodulation of the heartR01HL162921 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KALYANAM SHIVKUMAR, Corey B Smith · 2023 to 2026
$3.4M
Investigation of Partial Electrical Nerve Block for Autonomic RegulationR01HL150136 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI VRABEC, TINA LOUISE · 2020 to 2024
$2.2M
NHLBI NIH HHS P01 HL164311NHLBI NIH HHS R01 HL150136NHLBI NIH HHS R01 HL162921NINDS NIH HHS U41 NS129436
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HeartHeart RateNerve BlockVagus NerveVagus Nerve StimulationAnimalsMaleRatsRats, Sprague-DawleySpecies SpecificitySwinecardiacclosed-loop controlelectrical nerve blockfuzzy logicheart rateneuromodulationvagus

Identifiers

PMID40367967
PMCPMC12108926

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.