Evidence map›Paper›PMID 40367066›Full record

ArticleJournal of the American Chemical Society2025

Decoding Potassium Homeostasis in Cancer Metastasis and Drug Resistance: Insights from a Highly Selective DNAzyme-Based Intracellular K

Zhenglin Yang, Xiangli Shao, Yuting Wu, Aritra Roy, Elijah Garcia, Annie Farrell, Shreestika Pradhan, Weijie Guo, Heather Gan, Zeynep Korkmaz and 2 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhenglin YangDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0003-2743-5779
Xiangli ShaoDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Yuting WuDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0003-3196-5916
Aritra RoyDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0009-0004-0923-4441
Elijah GarciaMcKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, United States.
Annie FarrellDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0009-0003-1023-9728
Shreestika PradhanDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0009-0005-5216-5004
Weijie GuoDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, United States.
Heather GanDepartment of Molecular Biosciences, University of Texas at Austin, Austin, Texas 78712, United States.
Zeynep KorkmazDepartment of Biomedical Engineering, University of Texas at Austin, Austin, Texas 78712, United States.
Emily AdamsDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.
Yi LuDepartment of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0003-1221-6709

Funding

Design and Selection of Novel Metalloenzymes for Biocatalysis, Bioimaging, and Genetic EngineeringR35GM141931 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yi Lu · 2021 to 2026
$3.5M
NIGMS NIH HHS R35 GM141931
6 · The paper itself

Abstract

Potassium ions (K

Indexed as

Biosensing TechniquesDNA, CatalyticDrug Resistance, NeoplasmPotassiumCell Line, TumorFluorescent DyesHomeostasisHumansNeoplasm MetastasisDNA, CatalyticFluorescent DyesPotassium

Identifiers

PMID40367066
PMCPMC12120826

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.