Evidence map›Paper›PMID 40367051›Full record

ArticlePloS one2025

Influence of open-top chambers induced climate warming on secondary metabolic profile of culturally and medicinally important plants of Himalaya, Karakoram and Hindukush.

Saira Karimi, Muhammad Ali Nawaz, Saadia Naseem, Zahid Ali

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saira KarimiDepartment of Biosciences, Plant Biotechnology & Molecular Pharming Lab, COMSATS University Islamabad (CUI), Islamabad, Pakistan.
Muhammad Ali NawazDepartment of Biological and Environmental Sciences, Qatar University, Doha, Qatar.ORCID https://orcid.org/0000-0001-5632-9014
Saadia NaseemDepartment of Biosciences, Plant Biotechnology & Molecular Pharming Lab, COMSATS University Islamabad (CUI), Islamabad, Pakistan.
Zahid AliDepartment of Biosciences, Plant Biotechnology & Molecular Pharming Lab, COMSATS University Islamabad (CUI), Islamabad, Pakistan.ORCID https://orcid.org/0000-0003-3935-6816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants native to colder climates, higher elevations, or semi-arid regions have more phenolic compounds in their organs. Faced with the current climate crisis, the effects of global heating with overgrazing pressure on natural pastures are not fully recognized in the Himalaya-Karakoram and Hindukush (HKH) region. The objective of this research was to investigate how biological active compound accumulation and concentration of high-elevation plants change under the influence of simulated climate warming which was induced by open-top chambers. The bioactive profiling plant species from experimental units were investigated through High-Performance Liquid Chromatography (HPLC), and compared with control. That revealed a significant increase in the major phenolic acid and flavonoid compounds (Rutin, Quercetin, Myricetin, Gallic Acid, and Kaempferol). The accumulation of other minor compounds, such as Vanillic Acid, Syringic Acid, Ferulic Acid, and Catechin, showed species-specific variation in concentration. The species-specific responses indicated the dominant and positive adaptation species such as P. macrophylla, A. rupestris, A. penduncularis, P. hololeuca, P. alpina, and under stress could accumulate more secondary metabolites, explaining their capacity for adaptation. These species' proliferation under a stressed climate and higher elevation with grazing pressure provides insightful information about their exploitation of phenolic compounds which may alter the environmental sustainability.

Indexed as

Climate ChangeGlobal WarmingMetabolomePlants, MedicinalSecondary MetabolismChromatography, High Pressure LiquidFlavonoidsGallic AcidHydroxybenzoatesIndiaPhenolsFlavonoidsGallic AcidHydroxybenzoatesphenolic acidPhenols

Identifiers

PMID40367051
PMCPMC12077716

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.