Evidence map›Paper›PMID 40366992›Full record

ArticleEpidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil2025

Spatial analysis of risk areas of congenital anomalies in Brazil, 2012-2021.

Suzana de Souza, Clarissa Gutierrez Carvalho, Lavinia Schuler-Faccini

Abstract read
In one paragraph

Article in Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Temporal and spatial trends in isolated gastroschisis: a population-based study in a middle-income setting.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  2. Article
  3. Article
  4. Impact of congenital anomalies on infant mortality in the 14th Health Region of Paraná, from 2010 to 2019.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Suzana de SouzaUniversidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0003-2092-3526
Clarissa Gutierrez CarvalhoUniversidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0002-2663-4197
Lavinia Schuler-FacciniUniversidade Federal do Rio Grande do Sul, Programa de Pós-graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil.ORCID http://orcid.org/0000-0002-2428-0460

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify areas at risk for congenital anomalies in Brazil, from 2012 to 2021.

methodTime series analysis using data from the Live Birth Information System. Prevalence of anomalies in the period was calculated according to immediate geographic region. Spatial analysis was performed by calculating the Global and Local Moran index and spatial scanning, with calculation of Relative Risk (RR) and p-value, for the risk areas.

resultsAreas at higher risk for anomalies were identified in the Northeast, Southeast, and Southern regions. The Northeast region had a higher number of clusters (n=31) and higher prevalence of nervous system anomalies compared to the other regions (9.7/10,000 live births). The highest risk of anomalies compared to the other areas was found in the state of Paraíba (RR 2.4; p-value<0.001).

conclusionDisparities in the distribution of congenital anomalies were identified in Brazil, with risk areas in the Northeast, Southeast, and Southern regions.

Indexed as

Congenital AbnormalitiesBrazilHumansInfant, NewbornNervous System MalformationsPrevalenceRiskRisk FactorsSpatial Analysis

Identifiers

PMID40366992
PMCPMC12064163

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.