Evidence map›Paper›PMID 40366961›Full record

ArticleRadiology and oncology2025

Assessment of epicardial adipose tissue volume and carotid intima-media thickness in children with primary arterial hypertension by magnetic resonance imaging.

Nina Schweighofer, Natasa Marcun Varda, Primoz Caf, Mitja Rupreht, Vojko Kanic, Petra Povalej Brzan

Abstract read
In one paragraph

Article in Radiology and oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nina SchweighoferDepartment of Radiology, University Medical Centre Maribor, Maribor, Slovenia.
Natasa Marcun VardaDepartment of Pediatrics, University Medical Centre Maribor, Maribor, Slovenia.
Primoz CafDepartment of Radiology, University Medical Centre Maribor, Maribor, Slovenia.
Mitja RuprehtDepartment of Radiology, University Medical Centre Maribor, Maribor, Slovenia.
Vojko KanicDepartment of Cardiology, University Medical Centre Maribor, Maribor, Slovenia.
Petra Povalej BrzanMedical Faculty, University of Maribor, Maribor, Slovenia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEpicardial adipose tissue (EAT) is a biologically active visceral brown adipose tissue, which is irregularly distributed across myocardium. It has emerged as a potential modifiable cardiometabolic biomarker in adults, demonstrating pro-inflammatory properties with involvement in subclinical atherosclerosis. The increased thickness of the inner two layers of the carotid artery wall (intima and media) in childhood can pose as a risk of the development of atherosclerotic disease and its complications in adult life, representing additional potential biomarker. The purpose of our study was to evaluate a relation between EAT volume (EATV) and carotid intima-media thickness (cIMT) in children and adolescents who have been diagnosed with primary arterial hypertension (AH), utilizing magnetic resonance imaging (MRI). PATIENTS AND

methodsThe study included 72 children and adolescents, half of them had an established diagnosis of primary AH and the other half were matched healthy controls. The EATV and cIMT measurements were compared between the two groups and correlated with clinical, anthropometric and functional parameters.

resultsChildren diagnosed with AH exhibited a significantly higher EATV (16.5 ± 1.9 cm

conclusionsIncreased EATV and cIMT were found with MRI in hypertensive children compared to their healthy counterparts. EATV demonstrated a stronger association with hypertension than cIMT. EATV emerged as an independent predictor of cIMT.

Indexed as

Adipose TissueCarotid Intima-Media ThicknessHypertensionMagnetic Resonance ImagingPericardiumAdolescentCase-Control StudiesChildEpicardial Adipose TissueFemaleHumansMalearterial hypertensionatherosclerosischildrenepicardial adipose tissueintima-media thicknessmagnetic resonance imaging

Identifiers

PMID40366961
PMCPMC12182936

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.