Evidence map›Paper›PMID 40366710›Full record

ArticleBiological chemistry2025

TBK1 alleviates triptolide-induced nephrotoxic injury by up-regulating mitophagy in HK2 cells.

Xinxin Lu, Qionghui Huang, Zhaohui He, Huanjie Zhou, Zhenwei Chen, Youjian Zhou, Tiecheng Yang, Lang-Jing Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Biological chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xinxin LuDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.
Qionghui HuangDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.
Zhaohui HeDepartment of Urology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong, 518033, China.
Huanjie ZhouDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.
Zhenwei ChenDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.
Youjian ZhouDepartment of Pathology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong, 518033, China.
Tiecheng YangDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.
Lang-Jing ZhuDepartment of Nephrology, 575842 The Eighth Affiliated Hospital, Sun Yat-Sen University , Shenzhen, Guangdong, 518033, China.ORCID 0000-0003-0440-3600

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

DiterpenesKidneyMitophagyPhenanthrenesProtein Serine-Threonine KinasesUp-RegulationAnimalsCell LineCell SurvivalEpoxy CompoundsHumansMaleMembrane Potential, MitochondrialRatsRats, Sprague-DawleyDiterpenesEpoxy CompoundsPhenanthrenesProtein Serine-Threonine KinasesTBK1 protein, humantriptolidemitophagynephrotoxicityTBK1triptolide

Identifiers

PMID40366710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.