Evidence map›Paper›PMID 40366526›Full record

ArticleThe international journal of cardiovascular imaging2025

Left atrial filling index and stiffness index and its correlation to the duration of diabetes in patients with type II diabetes mellitus.

Fatma Elhady, Asmaa Ahmed Ali, Naglaa Shaban Elkholy, Eman A El-Mnakhly, Taher Said Abd Elkareem, Ahmed Galal, Mahmoud A Negm

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Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Fatma ElhadyCardiology Department, Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt. Fatma_elhady2013@yahoo.com.
Asmaa Ahmed AliCardiology Department, Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt.
Naglaa Shaban ElkholyInternal Medicine Department Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt.
Eman A El-MnakhlyInternal Medicine Department Faculty of Medicine (for Girls), Al-Azhar University, Cairo, Egypt.
Taher Said Abd ElkareemIslamic Center of Cardiology, Al-Azhar University, Cairo, Egypt.
Ahmed GalalCardiology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Mahmoud A NegmInternal Medicine Department Faculty of Medicine, Banha University, Nada Street 13518, Banha, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The left atrium (LA) has a vital role in diastolic function. One of the predictors of diastolic dysfunction (DD) is the LA reservoir strain. Beside this, stiffness of LA is considered another marker for LA function. Moreover, it is correlated with the degree of fibrosis than LA deformity itself. Aim of the study is to evaluate the LA phasic function, stiffness in patients with type II diabetes mellitus and whether these parameters could be the earlier markers of DD in T2DM. Also, to assess the effect of duration of T2DM on LA function. 103individuals, comprising 73patients with type II diabetes and 30 age and sex matched healthy control, depending on duration of diabetes, the patient group was classified into three groups, the first group (less than 10 years), group II (10-20 years) &group III (more than 20 years).2D-TTE was done for assessment of LA functions. Increased indexed LA volume (LAVI)&decreased LA phasic function in diabetic group(A). Elevated LA stiffness index earlier in diabetic patients (Group I) (p 0.02). There were significant differences between group I versus group II, III in LA function when measured by STE and between group I versus group II in LA stiffness index. We found that duration of diabetes is correlated negatively with LA function.LA filling index is positively correlated significantly with LA stiffness index p < 0.001, MV E, E/e', LAVI. The duration of diabetes was one of the predictors of LA dysfunction. Elevated LA stiffness with impaired its phasic function in diabetic patients. LA stiffness index and phasic function can be used as an earlier marker for diastolic dysfunction. Duration of diabetes has an effect on LA function and stiffness index.

Indexed as

Atrial Function, LeftDiabetes Mellitus, Type 2Diabetic CardiomyopathiesEchocardiography, DopplerAdultAgedCase-Control StudiesDiastoleFemaleFibrosisHeart AtriaHumansMaleMiddle AgedPredictive Value of TestsTime FactorsDuration of diabetesLA filling indexLA phasic functionLA stiffness index

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.