Observational studyEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025
Association between clinical outcome and microbiological findings in peritonsillar abscess - an observational study.
Observational study in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Peritonsillitis in primary care: patient characteristics and care pathways - a population-based registry study.BMC primary care · 2026Article
- The microbiological spectrum and clinical course of adolescents and adults with peritonsillar abscesses.Scientific reports · 2026Article
- Infections Caused by Fusobacterium Species: Microbiology, Clinical Syndromes and Management: A Narrative Review.Infectious diseases and therapy · 2026Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies on causative pathogens in peritonsillar abscesses have yielded varying results. However, Group A streptococci (GAS) and Fusobacterium necrophorum have been identified frequently. The aim of this study was to investigate pathogens in peritonsillar abscesses in patients tested for both ß-hemolytic streptococci and F. necrophorum, and to investigate associations between pathogens and clinical outcome.
methodThis retrospective observational study included all patients in the Skåne Region, Sweden (population 1.4 million) with a diagnosis of peritonsillar abscess between 2016 and 20, and in whom tests were performed for both ß-hemolytic streptococci (culture) and F. necrophorum (PCR). Exclusion criteria included previous (30 days) purulent complication to pharyngotonsillitis or antibiotic therapy. Chart review from 30 days prior to 6 months after the index visit was performed. Logistic regression was performed to evaluate the association between pathogens and complications, with negative microbiological findings set as reference category. Complications were defined as a composite outcome (0/1) of recurrent pharyngotonsillitis/peritonsillar abscess, other pharyngeal abscess or septic complications within 30 days (early), and 1-6 months (late).
resultsIn a total of 637 patients, F. necrophorum was identified in 210 (33%), GAS in 159 (28%) and GCS/GGS in 40 (6%) patients. F. necrophorum was most common in adolescents and young adults. Only F. necrophorum was associated with the development of either of early (OR 3.8 (2.0-7.1 95%CI)) and late complications (OR 2.5 (95%CI 1.3-4.9).
conclusionF. necrophorum was the most commonly identified pathogen in peritonsillar abscesses. It was also the only pathogen associated with the development of complications.
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