ArticleHead and neck pathology2025
Comparison of Histomorphometric Aspects between Oral Lichen Planus Lesions and Oral Lichenoid Lesions.
Article in Head and neck pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Digital Characterization of Clinical Subtypes of Oral Lichen Planus by Means of a Semi-Automated Morphometric Analysis: A Retrospective Observational Study.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionOral lichen planus (OLP) and oral lichenoid lesions (OLL) are considered potentially malignant oral disorders, presenting with similar clinical and histopathological manifestations that make differential diagnosis difficult and reinforce the need for new techniques for their evaluation.
objectiveThis study aimed to compare the histomorphometric characteristics of OLP and OLL. METHODOLOGY: This retrospective cross-sectional study was based on 30 histological sections of incisional biopsies of OLP and OLL stained with hematoxylin-eosin for the analysis of morphological parameters, such as keratosis, acanthosis, inflammatory infiltrate band, eosinophilic band, degeneration of the basal layer, involvement of the epithelium-chorion interface, and degree of subepithelial inflammatory infiltrate; and morphometric parameters, such as keratin thickness, distance from the basal layer to the epithelial surface, and thickness of the inflammatory infiltrate band. Chi-square and Fisher's exact tests were used to compare categorical variables and injury types. The t-test was used to compare morphometric variables between the two types of injury.
resultsThere was no significant association between the type of lesion and the clinical characteristics of the patients (p > 0.05). The degree of dysplasia, used as an inclusion criterion, was associated with lesion type (p = 0.0003). There were no significant differences between the morphometric variables evaluated for the two types of lesions (p > 0.05).
conclusionBased on the methodology used and the sample established for this study, there were clinical and histomorphometric similarities between OLP and OLL. This justifies further discussion on whether these lesions are a spectrum of presentations of the same condition or truly distinct conditions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.