Evidence map›Paper›PMID 40366403›Full record

ReviewPediatric nephrology (Berlin, Germany)2026

When our treatment is complicated: an overview of drug-induced acid-base disorders: part 1-acidosis.

Giulia Florio, Detlef Bockenhauer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Giulia FlorioDepartment of Cellular and Molecular Medicine, KUL Leuven, Louvain, Belgium.
Detlef BockenhauerDepartment of Cellular and Molecular Medicine, KUL Leuven, Louvain, Belgium. detlef.bockenhauer@uzleuven.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virtually every protein in our bodies binds protons, resulting in a specific electrical charge. If the surrounding proton concentration changes, such as in acidosis or alkalosis, the charge of the protein can change, as well, which in turn can affect protein folding and thus function. Therefore, disturbances of acid-base homeostasis can have serious clinical consequences, and for this reason, the blood pH is usually strictly controlled with the kidneys playing a major part in the long-term maintenance of acid-base homeostasis. Here we review alterations in blood pH that can occur as a side effect of medical treatments, with this first part discussing those resulting in acidosis.

Indexed as

Acid-Base EquilibriumAcid-Base ImbalanceAcidosisHumansHydrogen-Ion ConcentrationDrug treatmentMetabolic acidosisRespiratory acidosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.