Evidence map›Paper›PMID 40366338›Full record

Trial reportJournal of neurophysiology2025

Acute pain impairs retention of locomotor learning, regardless of the context of retention testing.

Samuel R Jackson, Ryan T Pohlig, Susanne M Morton

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samuel R JacksonDepartment of Physical Therapy, University of Delaware, Newark, Delaware, United States.ORCID 0009-0000-7155-8683
Ryan T PohligDepartment of Epidemiology, University of Delaware, Newark, Delaware, United States.
Susanne M MortonDepartment of Physical Therapy, University of Delaware, Newark, Delaware, United States.ORCID 0000-0002-7545-2189

Funding

Pain and Motor Learning in Older AdultsR01AG071585 · NIA · UNIVERSITY OF DELAWARE · PI Susanne M Morton · 2022 to 2026
$2.6M
Foundation for Physical Therapy Research (FPT)HHS | National Institutes of Health (NIH) 1R01AG071585NIA NIH HHS R01 AG071585
6 · The paper itself

Abstract

Our group and others have shown that the presence of an acute painful stimulus may interfere with retention of motor learning. Conversely, other evidence suggests this effect may not be truly due to pain, but due to a change in context when testing retention, i.e., testing retention in a nonpainful context when learning occurred in a painful context. Yet to our knowledge, no study has directly compared the retention of learning acquired under painful conditions with versus without a context change. To answer this question, we tested 30 young, healthy adults on a locomotor learning and retention paradigm. All participants walked on a treadmill with a monitor displaying distorted real-time visual feedback of step lengths to induce learning of an asymmetric stepping pattern. Retention was assessed 24 h later. Participants were randomized into one of three groups: one received no intervention; one received a painful stimulus during learning on

Indexed as

Acute PainLearningLocomotionRetention, PsychologyAdultFemaleHumansMaleYoung Adultconsolidationgaitlocomotionmotor learningpain interference

Identifiers

PMID40366338
PMCPMC12416618

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.