Evidence map›Paper›PMID 40366172›Full record

ArticleJournal of virology2025

Manish Chauhan, Peter E Martinak, Benjamin M Hollenberg, Alan G Goodman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Insects · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

  • Update of
    2024
5 · Who and what money

Authors and funding

4 authors.

Manish ChauhanSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0003-2639-731X
Peter E MartinakSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Benjamin M HollenbergSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Alan G GoodmanSchool of Molecular Biosciences, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0001-6394-332X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Toll pathway plays a pivotal role in innate immune responses against pathogens. The evolutionarily conserved pattern recognition receptors (PRRs), including Toll-like receptors (TLRs), play a crucial role in recognition of pathogen-associated molecular patterns (PAMPs). The IMPORTANCE: Insects rely on innate immunity and RNA interference (RNAi) to combat viral infections. Our study underscores the pivotal role of

Indexed as

Drosophila melanogasterDrosophila ProteinsPicornaviridaeToll-Like Receptor 9AnimalsCell LineDicistroviridaeEndosomesImmunity, InnateProto-Oncogene Proteins c-aktRibonuclease IIIRNA, Double-StrandedRNA HelicasesRNA, ViralSignal TransductionVirus ReplicationDCR-2 protein, DrosophilaDrosophila ProteinsProto-Oncogene Proteins c-aktRibonuclease IIIRNA, Double-StrandedRNA HelicasesRNA, ViralToll-Like Receptor 9AKTDCVDicer2dsRNAendosomeJAK/STAT

Identifiers

PMID40366172
PMCPMC12172494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.