Evidence map›Paper›PMID 40366151›Full record

ArticleJournal of bacteriology2025

Loss of LasR function leads to decreased repression of

Amy Conaway, Dallas L Mould, Igor Todorovic, Deborah A Hogan

Abstract read
In one paragraph

Article in Journal of bacteriology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Microbiology spectrum · 2026
    Article
  2. mSphere · 2026
    Article
  3. Gnotobiotic growth and phosphorus limitation of Arabidopsis thaliana and co-occurring microbes on phosphated iron oxides.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  4. Review
  5. mBio · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Amy ConawayDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-4174-2268
Dallas L MouldDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Igor TodorovicDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Deborah A HoganDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.ORCID 0000-0002-6366-2971

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Fred W Kolling IV · 1985 to 2026
$91.3M
Understanding the role of RNA-binding protein mutations in cancerP20GM113132 · NIGMS · DARTMOUTH COLLEGE · PI LACEFIELD, SONI · 2016 to 2025
$25.9M
Translational Research CoreP30DK117469 · NIDDK · DARTMOUTH COLLEGE · PI DEAN R MADDEN · 2018 to 2026
$13.9M
Dartmouth Cystic Fibrosis Training ProgramT32HL134598 · NHLBI · DARTMOUTH COLLEGE · PI George A. O'Toole · 2017 to 2026
$1.7M
Cross-fed metabolites modulate Pseudomonas aeruginosa fitnessF31AI179113 · NIAID · DARTMOUTH COLLEGE · PI CONAWAY, AMY CAROLYN · 2024 to 2025
$99k
Cystic Fibrosis Foundation GREEN19G0, BOMBER24P0NCI NIH HHS 5P30CA023108NCI NIH HHS P30 CA023108NHLBI NIH HHS T32 HL134598NIAID NIH HHS F31 AI179113NIDDK NIH HHS P30 DK117469NIGMS NIH HHS P20 GM113132NIGMS NIH HHS P20GM113132NIH HHS NHLBI T31HL134598, NIDDK P30-D117469, F31AI179113
6 · The paper itself

Abstract

The

Indexed as

Bacterial ProteinsGene Expression Regulation, BacterialPhosphatesPseudomonas aeruginosaTrans-ActivatorsMutationQuorum SensingBacterial ProteinsLasR protein, Pseudomonas aeruginosaPhoB protein, BacteriaPhosphatesTrans-ActivatorsCbrBCrcLasRphenazinesPhoBPhoRphosphate scavengingPseudomonas aeruginosaquorum sensingRhlR

Identifiers

PMID40366151
PMCPMC12186492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.