Evidence map›Paper›PMID 40366117›Full record

ArticleTurkish journal of anaesthesiology and reanimation2025

Should I Change Anticoagulane in Veno-Venous ECMO?

Rabia Yılmaz, Murat Arslan, Deniz Özel Bilgi, Zafer Çukurova

Abstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rabia YılmazUniversity of Health Sciences Türkiye, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Anaesthesiology and Reanimation Critical Care, İstanbul, Türkiye.ORCID 0000-0003-1707-4607
Murat ArslanUniversity of Health Sciences Türkiye, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Anaesthesiology and Reanimation Critical Care, İstanbul, Türkiye.ORCID 0000-0002-0499-6859
Deniz Özel BilgiUniversity of Health Sciences Türkiye, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Anaesthesiology and Reanimation Critical Care, İstanbul, Türkiye.ORCID 0000-0003-3594-5816
Zafer ÇukurovaUniversity of Health Sciences Türkiye, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Clinic of Anaesthesiology and Reanimation Critical Care, İstanbul, Türkiye.ORCID 0000-0002-8893-3977

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Due to a lack of high-quality data to guide anticoagulation therapy in extracorporeal membrane oxygenation (ECMO) patients, there is significant variation in practice among centers. We aimed to investigate the safety, anticoagulation efficacy, and cost-effectiveness of using bivaluridine as a primary anticoagulant without unfractionated heparin (UFH) in ECMO patients. Methods: The study population included patients undergoing Veno-Venous ECMO for acute respiratory distress syndrome. A total of 56 patients were evaluated, 25 were on UFH and 31 were on bivalirudin. Results: There was no significant difference between the time to reach the target activated partial thromboplastin time (aPTT) interval [6 (3.5-11) UFH, 9 (4-19) bivalirudin, P=0.287]. There was no significant difference between the percentage of time spent in the target aPTT interval (61.48±14.72 UFH, 62.65±11.99 bivaluridine, Conclusion: The use of bivaluridine as a primary anticoagulant does not lead to any decrease in anticoagulant efficacy.

Indexed as

AnticoagulantbivaluridinbleedingECMOthrombosis

Identifiers

PMID40366117
PMCPMC12288425

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.