Evidence map›Paper›PMID 40366090›Full record

ReviewJournal of clinical laboratory analysis2025

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections.

Shuangwen Xiao, Wei Zuo, Qing Xiang, Yafeng Xie, Yongjian Xiao

Abstract readReview
In one paragraph

Review in Journal of clinical laboratory analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuangwen XiaoDepartment of Clinical Laboratory, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Wei ZuoDepartment of Clinical Laboratory, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Qing XiangDepartment of Clinical Laboratory, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Yafeng XieDepartment of Clinical Laboratory, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.
Yongjian XiaoDepartment of Clinical Laboratory, The Second Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, China.ORCID https://orcid.org/0009-0000-2402-569X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs) are a major threat to global health, and the emergence of antibiotic-resistant strains has made therapeutic strategies more complex. Antimicrobial peptides (AMPs) are a ubiquitous class of natural compounds that are expected to be an alternative to conventional antibiotics due to their broad spectrum of activity and lower propensity for resistance, promising alternatives to conventional antibiotics.

objectiveTo emphasize the importance of antimicrobial peptides in the fight against STIs and to review recent advances in AMPs for the treatment and prevention of STIs.

methodsThis article focuses on reviewing the progress of research on AMPs in the treatment and prognosis of STIs such as gonorrhea, HIV, HPV, and chlamydia, and discusses the challenges and future directions of the field.

resultsAMPs have great potential in the prevention and treatment of STIs. However, AMPs for the treatment of STIs face challenges such as enzymatic degradation, safety and high cost, while nanotechnology and peptide modification are expected to enhance the stability and bioavailability of AMPs.

conclusionAMPs have the potential to become an important tool for the treatment of STIs with further research and technological innovation.

Indexed as

Antimicrobial PeptidesSexually Transmitted DiseasesHumansAntimicrobial Peptidesantimicrobial peptidesChlamydiagonorrheaHIVHSVsexually transmitted infections

Identifiers

PMID40366090
PMCPMC12144605

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.