Evidence map›Paper›PMID 40366057›Full record

ArticleJournal of clinical laboratory analysis2025

Analysis of Differentially Expressed Proteins Involved in Shrimp and Crab Allergies.

Ruhong Tan, Xiwen Wei, Jiacheng Zhong, Yuanbin Wang, Qing Yu

Abstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruhong TanDepartment of Clinical Laboratory, Foshan Women and Children Hospital, Foshan, Guangdong, P. R. China.
Xiwen WeiDepartment of Clinical Laboratory, Foshan Women and Children Hospital, Foshan, Guangdong, P. R. China.
Jiacheng ZhongDepartment of Clinical Laboratory, Foshan Women and Children Hospital, Foshan, Guangdong, P. R. China.
Yuanbin WangDepartment of Clinical Laboratory, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen, Guangdong, P. R. China.
Qing YuDepartment of Clinical Laboratory, Shenzhen Mental Health Center/Shenzhen Kangning Hospital, Shenzhen, Guangdong, P. R. China.ORCID https://orcid.org/0000-0002-7322-7180

Funding

Foshan Science and Technology Innovation Projects 1920001000245Natural Science Foundation of Guangdong Province 2019A1515110044Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties SZGSP013
6 · The paper itself

Abstract

backgroundShrimp and crab allergies have garnered increasing attention in recent years. Unlike many other food allergies, they are less likely to be outgrown by children and tend to trigger more severe allergic symptoms. The underlying mechanisms that lead to these phenomena have not yet been fully elucidated.

methodsWe used proteomics iTRAQ technology to identify differentially expressed proteins in shrimp and crab allergic patients and normal controls.

resultsNinety differentially expressed proteins, including 82 upregulated proteins and 8 downregulated proteins, were identified. Furthermore, MRC2 was validated to be upregulated in shrimp and crab allergic patients by ELISA.

conclusionThese findings have established a comprehensive proteomics map of shrimp and crab allergies, laying the foundation for further analysis of the pathogenesis and regulatory network of shrimp and crab allergies.

Indexed as

BrachyuraFood HypersensitivityPenaeidaeShellfish HypersensitivityAdultAnimalsCase-Control StudiesChildFemaleHumansMaleProteomicsiTRAQMRC2shrimp and crab allergies

Identifiers

PMID40366057
PMCPMC12179796

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.