ArticleNucleic acids research2025
MAGNETIC: a web server to fetch gene network based on motif distribution in promoters.
Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Our web server MAGNETIC (Motif Associated Gene NETworks in Chromosomes) allows users to search the human genome for correlations between promoter regions of genes. The correlations take into consideration the similarity of the abundance of 5/6-mer motifs in gene promoters. The promoters could be 1, 2, or 6 kb upstream of the gene start site. Genes with similar motif abundances are linked to form a gene regulatory network. These networks could help determine or even discover gene networks of input genes. Our database could also be searched by motifs (including degenerate positions). The results identify the abundance of the motif in the promoters of all genes. The promoters where the motif is found in high abundance are likely to be target binding sites of a protein that recognizes the input sequence. MAGNETIC can also determine the similarity between gene promoters at the scale of whole chromosomes. We have showcased our server using a few examples that involve the consensus recognition motif of the transcription factor, Myc, and the genes it regulates. We have identified putative new targets of Myc and also found instances where Myc could only indirectly regulate genes. This server could help make important connections between genes and give insights into gene regulation and function.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.