Evidence map›Paper›PMID 40365566›Full record

ArticleFrontiers in plant science2025

Analysis of differences in cigar tobacco leaves from different regions based on GC-IMS and LC-MS metabolomics techniques.

Dan Chen, Liang Feng, Haowei Sun, Risheng Zhong, Chunqiong Wang, Xiaowei Zhang, Ke Zhang, Ling-Duo Bu, Wanlong Yang, Kai Liu and 2 more

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dan ChenYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Liang FengBeijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing, China.
Haowei SunYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Risheng ZhongBeijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing, China.
Chunqiong WangYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Xiaowei ZhangYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Ke ZhangYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Ling-Duo BuYunnan Tobacco Company, Yuxi, Yunnan, China.
Wanlong YangYunnan Oriental Tobacco Company, Ltd., Kunming, Yunnan, China.
Kai LiuYunnan Tobacco Quality Inspection & Supervision Station, Kunming, Yunnan, China.
Haitao ChenBeijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing, China.
Shuqi WangBeijing Key Laboratory of Flavor Chemistry, Beijing Technology and Business University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate the differences in volatile compound composition and metabolites in cigar tobacco leaves from different regions of Yunnan. Cigar tobacco leaves from various regions and varieties in Yunnan were analysed using gas chromatography-ion mobility spectrometry and non-targeted metabolomics techniques. Results showed that 109 volatile compounds, including 26 esters, 17 aldehydes, 14 alcohols, 14 ketones, 9 olefins, 5 pyrazines, 4 ethers, 4 acids and 16 others, were identified in cigar tobacco leaves. Through GC-IMS analysis of volatile compounds in cigar tobacco from 10 regions, 1-methylethyl acetate, diethyl acetal, butanal, 1-hexanol, pyridine, and toluene were identified as common compounds with consistently high content across all regions. For regional characteristics, BS-Y1-1 is featured by high levels of 2,3-diethyl-6-methylpyrazine and phenylacetaldehyde; PE-Y2 shows the highest content of 3-methyl-1-pentanol; and WS-Y38 is characterised by significantly high levels of butan-2-one. These differences reflect the uniqueness of volatile components in cigar tobacco from different producing areas. The volatile compounds in Yunnan cigar tobacco leaves were greatly influenced by the origin and species, with cigar tobacco leaves from the Baoshan region differing from those in other regions. According to the Kyoto Encyclopedia of Genes and Genomes enrichment analysis, amino acid metabolism, nucleotide metabolism and glyoxylate and dicarboxylate metabolism were the main metabolic pathways, and their metabolites contributed to the formation of flavour in Yunnan cigar tobacco leaves.

Indexed as

chemical compositionchemometricsLC-MSregional differencesvolatile compounds

Identifiers

PMID40365566
PMCPMC12069380

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