Evidence map›Paper›PMID 40365527›Full record

ArticleSleep advances : a journal of the Sleep Research Society2025

Facility-measured nocturnal hypoxemia and sleep among adults with long COVID versus age- and sex-matched healthy adults: a preliminary observational study.

Haoqi Sun, Rammy Dang, Monika Haack, Kristine Hauser, Jennifer Scott-Sutherland, M Brandon Westover, Sairam Parthasarathy, Susan Redline, Robert J Thomas, Janet M Mullington

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In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haoqi SunDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0002-5041-8312
Rammy DangDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0003-4014-6429
Monika HaackDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0001-6214-4294
Kristine HauserClinical and Translational Research Center, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Jennifer Scott-SutherlandDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
M Brandon WestoverDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0003-4803-312X
Sairam ParthasarathyArizona Respiratory Center and Department of Medicine, University of Arizona, Tucson, AZ, USA.
Susan RedlineDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-6585-1610
Robert J ThomasDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0002-5575-3953
Janet M MullingtonDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA.ORCID https://orcid.org/0000-0002-9156-9424

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study Objectives: Persistent post-acute sequelae of SARS-CoV-2 infection, i.e. long COVID, impacts multiple organ systems. While lower blood oxygen is expected when SARS-CoV-2 infects the lungs, hypoxia without pulmonary symptoms may continue after the acute phase. Ventilation and blood oxygen are more vulnerable during sleep, but nocturnal hypoxemia hasn't been studied in people with long COVID in a facility setting using gold-standard polysomnography (PSG). Methods: We conducted an observational study with 50 participants (25 long COVID, 25 age-sex-matched healthy controls) using in-laboratory overnight PSG. We calculated the average SpO Results: We found that average SpO Conclusions: The results suggest that long COVID had a persistent lower nocturnal blood oxygen saturation, and support the need for a large-scale study of nocturnal hypoxemia in people with long COVID compared to the general population.

Indexed as

long COVIDnocturnal hypoxemiaoxygen desaturationpolysomnographysleepSpO2

Identifiers

PMID40365527
PMCPMC12070477

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.