Evidence map›Paper›PMID 40365492›Full record

ArticleFrontiers in medicine2025

Intermittent hypoxia index: a new indicator for assessing the degree of intermittent hypoxia in obstructive sleep apnea.

Kui Xie, Xiaoqing Tang, Jiacheng Zhou, Xiang Liu, Yunyun Zhang, Xiaochuan Cui

Abstract read
In one paragraph

Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kui XieDepartment of General Practice and Sleep Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Xiaoqing TangDepartment of General Practice and Sleep Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Jiacheng ZhouDepartment of General Practice and Sleep Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Xiang LiuAdvanced Information Materials Research Center, School of Physics and Materials Science, Guangzhou University, Guangzhou, China.
Yunyun ZhangDepartment of General Practice and Sleep Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.
Xiaochuan CuiDepartment of General Practice and Sleep Center, The Affiliated Wuxi People's Hospital of Nanjing Medical University, Wuxi People's Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: In order to objectively and accurately evaluate the degree of nocturnal intermittent hypoxia (IH) in patients with obstructive sleep apnea (OSA), we developed the Newton quadrature low oxygen load assessment system (NLAS) to seek a new, quantifiable, comprehensive evaluation index of intermittent hypoxia (intermittent hypoxia index, IHI). Methods: Demographic characteristics, anthropometric measurements, and polysomnography (PSG) parameters [oxygen desaturation index (ODI), lowest oxygen saturation (LSpO Results: Among the 732 patients with OSA, IHI showed significant correlations with T90 ( Conclusion: This study demonstrates that IHI calculated using NLAS covers various dimensions of IH indices in OSA patients undergoing multi-channel sleep monitoring. It correlates with parameters such as T90, LSpO

Indexed as

intermittent hypoxiaintermittent hypoxia indexNewton-cotes formulaNewton quadrature low oxygen load assessment systemobstructive sleep apnea

Identifiers

PMID40365492
PMCPMC12069030

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.