Evidence map›Paper›PMID 40365460›Full record

ArticleFrontiers in toxicology2025

Associations of environmental pollution with pro-oxidant, antioxidant and inflammatory markers in pregnant mothers and newborns.

Antonin Ambroz, Jiri Klema, Andrea Rossnerova, Alena Milcova, Anna Pastorkova, Jana Pulkrabova, Ondrej Parizek, Veronika Gomersall, Tomas Gramblicka, Jaroslav Zelenka and 7 more

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In one paragraph

Article in Frontiers in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Antonin AmbrozDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Jiri KlemaDepartment of Computer Science, Faculty of Electrical Engineering, Czech Technical University in Prague, Prague, Czechia.
Andrea RossnerovaDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Alena MilcovaDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Anna PastorkovaDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Jana PulkrabovaDepartment of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Ondrej ParizekDepartment of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Veronika GomersallDepartment of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Tomas GramblickaDepartment of Food Analysis and Nutrition, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Jaroslav ZelenkaDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Tomas RumlDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Nikola VrzackovaDepartment of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, University of Chemistry and Technology, Prague, Czechia.
Milos VeleminskyFaculty of Health and Social Sciences, University of South Bohemia, Ceske Budejovice, Czechia.
Newroz HasanDepartment of Obstetrics and Gynaecology, Hospital Karvina-Raj, Karvina, Czechia.
Jan TopinkaDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Radim J Sram *Department of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.
Pavel RossnerDepartment of Toxicology and Molecular Epidemiology, Institute of Experimental Medicine CAS, Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to analyze the variables that modify the levels of oxidative DNA damage and lipid peroxidation in non-smoking mothers and their newborns from environmentally distinct localities of the Czech Republic: Ceske Budejovice (CB, an agricultural region) and Karvina (an industrial region). Personal, socio-economic and medical data, concentrations of particulate matter of aerodynamic diameter < 2.5 µm (PM2.5) and benzo[a]pyrene (B[a]P) in the ambient air, the activities of antioxidant mechanisms (superoxide dismutase, catalase, glutathione peroxidase) and antioxidant capacity), the levels of pro-inflammatory cytokines, the concentrations of persistent organic pollutants (POPs) in blood plasma/cord blood plasma and urinary levels of polycyclic aromatic hydrocarbons metabolites (OH-PAHs) were investigated as parameters potentially affecting the markers of DNA oxidation (8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxodG) and lipid peroxidation (15-F

Indexed as

antioxidant response and inflammatory cytokinesenvironmental pollutionlipid peroxidationmaternal exposure to newbornoxidative DNA damage

Identifiers

PMID40365460
PMCPMC12069330

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.