Sulfated chitosan directs the recovery of ischemic stroke by attenuating the inflammatory cascade.

Zehua Gao, Xuanlin Wang, Qiyong Mei, Tong Shen, Jing Wang, Changsheng Liu

Abstract read

In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed, 1 pooled it

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

Emerging regenerative strategies for spinal cord injury: exosome-derived mechanisms and therapeutic insights.Frontiers in neuroscience · 2025
Pooled it
The spatiotemporal dynamic evolution of post-stroke neuroinflammation: energy metabolism mechanisms of acute response and chronic progression.Frontiers in pharmacology · 2026
Review
Integrative bioinformatics and machine learning approaches identify inflammation-related genes and drug candidates for future preclinical validation in ischemic stroke.BMC neurology · 2025
Article
Macrophage polarization: molecular mechanisms, disease implications, and targeted therapeutic strategies.Frontiers in immunology · 2025
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zehua GaoThe State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Xuanlin WangThe State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Qiyong MeiDepartment of Neurosurgery, Changzheng Hospital, Naval Medical University, Shanghai 200003, China.

Tong ShenThe State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Jing WangThe State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.

Changsheng LiuKey Laboratory for Ultrafine Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChitosanInflammationIschemic StrokeAnimalsApoptosisCytokinesDisease Models, AnimalHumansMacrophagesMaleMiceMice, Inbred C57BLNeutrophilsSignal TransductionSTAT3 Transcription FactorChitosanCytokinesSTAT3 Transcription Factorinflammationischemia strokeneutrophilsulfated chitosan

Identifiers

PMID40365292

DOI10.7150/thno.111681

PMCPMC12068298

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.