Evidence map›Paper›PMID 40365278›Full record

ArticleTheranostics2025

Shh agonist enhances maturation in homotypic Lgr5-positive inner ear organoids.

Nathaniel T Carpena, So-Young Chang, Seyoung Mun, Kyung Wook Kim, Hyun C Yoon, Phil-Sang Chung, Ji-Hun Mo, Jin-Chul Ahn, Ji On Park, Kyudong Han and 3 more

Abstract read
In one paragraph

Article in Theranostics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nathaniel T CarpenaDepartment of Medical Laser, Graduate School of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
So-Young ChangBeckman Laser Institute Korea, Dankook University, Cheonan 31116, Republic of Korea.
Seyoung MunDepartment of Cosmedical & Materials, Dankook University, Cheonan 31116, Republic of Korea.
Kyung Wook KimDepartment of Orthopaedic Surgery, Dankook University Hospital, Dankook University College of Medicine, Cheonan, 31116, Korea.
Hyun C YoonDepartment of Molecular Science & Technology, Ajou University, Suwon, 443749, Republic of Korea.
Phil-Sang ChungBeckman Laser Institute Korea, Dankook University, Cheonan 31116, Republic of Korea.
Ji-Hun MoDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Jin-Chul AhnBeckman Laser Institute Korea, Dankook University, Cheonan 31116, Republic of Korea.
Ji On ParkMedical Laser Research Center, Dankook University, Cheonan 31116, Republic of Korea.
Kyudong HanDepartment of Microbiology, College of Science & Technology, Dankook University, Cheonan 31116, Republic of Korea.
Ji Eun ChoiDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Jae Yun JungDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Min Young LeeBeckman Laser Institute Korea, Dankook University, Cheonan 31116, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ear, InnerHedgehog ProteinsOrganoidsReceptors, G-Protein-CoupledAnimalsCell DifferentiationCoculture TechniquesHair Cells, AuditoryMiceMice, Inbred C57BLSpiral GanglionStem CellsStereociliaHedgehog ProteinsLgr5 protein, mouseReceptors, G-Protein-CoupledShh protein, mouseinner ear organoidLgr5microelectrode arrayRNA sequencingsonic hedgehog

Identifiers

PMID40365278
PMCPMC12068299

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.