ArticleBrain communications2025
Altered functional connectivity strength between structurally and functionally affected brain regions in visual snow syndrome.
Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Visual snow syndrome as a neuropsychiatric network disorder: clinical features, mechanisms, and therapeutic perspectives.Journal of neurology · 2026Review
- Unmasking the noise: aberrant cortical oscillations in visual snow syndrome.The journal of headache and pain · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Visual snow syndrome (VSS) is a neurological disorder that is predominantly characterized by persistent, dynamic visual disturbances, experienced across the entire visual field. Earlier research highlighted the significance of distinct brain regions, exhibiting alterations in both anatomical structure and functional characteristics. To further investigate the functional role of these regions, we examined the resting-state connectivity between these areas in individuals with VSS and the relation with VSS symptoms and oculomotor measures of visual processing. Forty patients with VSS (53% females; age = 33.2 ± 10.1 years; 22 with migraine) and 60 healthy controls (58% females; age = 32.0 ± 9.2 years) were scanned using 7 Tesla MRI system. High spatial and temporal resting-state (RS) functional (TR = 800 ms, 1.6 mm isotropic) and anatomical (MP2RAGE, 0.75 mm isotropic) images were acquired. Resting-state data were pre-processed (motion correction, temporal filtering and spatial smoothing), functional connectivity was calculated between regions of interest and compared between groups. Significant metrics were compared with VSS patients with and without migraine and correlated with oculomotor measures (prosaccade and anti-saccade latencies), number of VSS symptoms, self-rated VSS intensity and perceived disruptiveness. Compared to healthy controls, VSS patients demonstrated significantly higher connectivity between the supramarginal gyrus and lateral occipital cortex (
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