Evidence map›Paper›PMID 40365093›Full record

ReviewBreathe (Sheffield, England)2025

An update on diagnosis and treatments of childhood interstitial lung diseases.

Honorata Marczak, Katarzyna Krenke, Matthias Griese, Julia Carlens, Elias Seidl, Carlee Gilbert, Nagehan Emiralioglu, Alba Torrent-Vernetta, Brigitte Willemse, Ralph Epaud and 5 more

Abstract readReview
In one paragraph

Review in Breathe (Sheffield, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Old and emerging therapies for childhood interstitial lung disease (chILD): a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Occult Childhood Interstitial Lung Disease.Balkan medical journal · 2026
    Article
  9. Article
  10. Pulmonary alveolar proteinosis andFrontiers in pediatrics · 2026
    Article
  11. [Childhood interstitial lung disease].Radiologie (Heidelberg, Germany) · 2025
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Honorata MarczakDepartment of Pediatric Pneumology and Allergy, Medical University of Warsaw, Warsaw, Poland.
Katarzyna KrenkeDepartment of Pediatric Pneumology and Allergy, Medical University of Warsaw, Warsaw, Poland.ORCID https://orcid.org/0000-0002-8370-784X
Matthias GrieseDepartment of Paediatric Pneumology, Dr von Hauner Children's Hospital, German Centre for Lung Research, University of Munich, Munich, Germany.ORCID https://orcid.org/0000-0003-0113-912X
Julia CarlensClinic for Pediatric Pneumology, Hannover Medical School, Hannover, Germany.ORCID https://orcid.org/0000-0001-8578-864X
Elias SeidlDivision of Respiratory Medicine, University Children's Hospital Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0001-6610-3756
Carlee GilbertInstitute of Population Health, University of Liverpool, Liverpool, UK.ORCID https://orcid.org/0000-0002-5340-5728
Nagehan EmiraliogluDepartment of Pediatric Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.ORCID https://orcid.org/0000-0002-1405-8401
Alba Torrent-VernettaPediatric Allergy and Pulmonology Section, Department of Pediatrics, Vall d'Hebron Hospital Universitari, Vall d'Hebron Barcelona Hospital Campus, Universitat Autònoma de Barcelona, Barcelona, Spain.ORCID https://orcid.org/0000-0002-3575-2427
Brigitte WillemseDepartment of Pediatric Pulmonology and Pediatric Allergology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Ralph EpaudCentre Hospitalier Intercommunal de Créteil, Service de Pédiatrie Générale, Centre de référence des maladies respiratoires rares, Créteil, France.ORCID https://orcid.org/0000-0003-3830-1039
Celine DelestrainCentre Hospitalier Intercommunal de Créteil, Service de Pédiatrie Générale, Centre de référence des maladies respiratoires rares, Créteil, France.
Camille LouvrierDepartment of Molecular Genetics, Armand Trousseau Hospital, Assistance Publique Hôpitaux de Paris, Paris, France.ORCID https://orcid.org/0000-0003-2105-1117
Václav KouckýDepartment of Paediatrics, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.
Nadia NathanLaboratory of Childhood Genetic Diseases, Inserm UMR_S933, Sorbonne University, Armand Trousseau Hospital, Paris, France.ORCID https://orcid.org/0000-0001-5149-7975
ERS CRC chILD-EU group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Childhood interstitial lung diseases (chILDs) are rare and heterogeneous disorders associated with significant morbidity and mortality. The clinical presentation of chILD typically includes chronic or recurrent respiratory signs and symptoms with diffuse radiographic abnormalities on chest imaging. Diagnosis requires a structured, multi-step approach. Treatment options are limited, with disease-specific therapies available only in selected cases and management relying primarily on supportive care. Awareness of chILDs has been steadily increasing. New diagnoses, advanced diagnostic tests, and novel treatments are emerging each year, highlighting the importance of collaborative, multidisciplinary teams in providing comprehensive care for children and families affected by these complex conditions. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review provides an updated overview of the diagnostic approach and management strategies for chILDs.

Identifiers

PMID40365093
PMCPMC12070201

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.