Evidence map›Paper›PMID 40365089›Full record

ArticleJSLS : Journal of the Society of Laparoendoscopic Surgeons

Comparative Outcomes of Laparoscopic Radical Hysterectomy and Nerve-Sparing Technique in Cervical Cancer Patients.

Shailesh Puntambekar, Maitreyee Parulekar, Sneha Venkateswaran, Saranya Naidu, Madhavi Patil, Kshitij Manerikar, Suyog Bharambe, Mihir Chitale, Mangesh Panse, Ravindra Sathe and 1 more

Abstract readComparative Study
In one paragraph

Article in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Shailesh PuntambekarConsultant Oncosurgeon and Director, Galaxy Care Hospital, Pune, Maharashtra, India. (Dr. Puntambekar).
Maitreyee ParulekarFellow in Minimally Invasive Gynecologic Surgery, Department of Gynecology, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Parulekar, Venkateswaran, Naidu, and Patil).
Sneha VenkateswaranFellow in Minimally Invasive Gynecologic Surgery, Department of Gynecology, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Parulekar, Venkateswaran, Naidu, and Patil).
Saranya NaiduFellow in Minimally Invasive Gynecologic Surgery, Department of Gynecology, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Parulekar, Venkateswaran, Naidu, and Patil).
Madhavi PatilFellow in Minimally Invasive Gynecologic Surgery, Department of Gynecology, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Parulekar, Venkateswaran, Naidu, and Patil).
Kshitij ManerikarConsultant Oncosurgeon, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Manerikar and Chitale).
Suyog BharambeConsultant Endoscopic Surgeon, Galaxy Care Hospital, Pune, Maharashtra, India. (Dr. Bharambe).
Mihir ChitaleConsultant Oncosurgeon, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Manerikar and Chitale).
Mangesh PanseConsultant Surgeon, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Panse and Sathe).
Ravindra SatheConsultant Surgeon, Galaxy Care Hospital, Pune, Maharashtra, India. (Drs. Panse and Sathe).
Seema PuntambekarConsultant Gynecologist, Galaxy Care Hospital, Pune, Maharashtra, India. (Dr. Puntambekar).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Aim was to analyze and compare the oncological outcomes, genitourinary quality of life (QOL), disease-free survival (DFS), and overall survival (OS) of patients treated by laparoscopic radical hysterectomy (LRH) and laparoscopic nerve-sparing radical hysterectomy (LNSRH) for early cervical cancer. Design: Retrospective study in patients of carcinoma cervix FIGO (2009) grade 1A to 2A1 from January 1, 2016 until the publication of Laparoscopic Approach to Cervical Cancer (LACC) trial in 2018, after which only 1A and 1B1 were included up to December 31, 2020. Setting: Total of 285 patients operated over 5 years at the center were placed in 2 groups, LRH and LNSRH, based on surgical approach. Measurements: Tumor characteristics, clinical profile, tumor clearance, histopathology, adjuvant treatment, period of follow-up and recurrence were compared. The QOL was analyzed in terms of bladder and sexual function. Results: LNSRH group had significantly faster recovery of bladder (lesser number of days required for PVR <50 mL, quicker catheter removal time, less requirement of self-catheterization, less incidence of urinary retention and incontinence) and sexual function as compared to LRH group. There was no significant difference in radicality of the procedure. None of them had vault recurrences. DFS at 5 years for LRH and LNSRH was 95.3% and 94.1%, respectively. OS at 2 years for LRH and LNSRH was 95.9% and 96.3%, respectively, whereas the OS at 5 years was 95.3% and 94.1%, respectively. Conclusion: LNSRH group had significantly better genitourinary QOL as compared to the LRH group without compromising on oncological clearance. The survival is comparable to the results of open surgery in LACC trial.

Indexed as

HysterectomyLaparoscopyOrgan Sparing TreatmentsUterine Cervical NeoplasmsAdultAgedFemaleHumansMiddle AgedQuality of LifeRetrospective StudiesSurvival RateTreatment OutcomeEarly cervical cancerLaparoscopic approach to cervical cancer (LACC)Laparoscopic nerve sparing radical hysterectomy (LSNRH)Laparoscopic radical hysterectomy (LRH)Minimally invasive surgery in cervical cancer

Identifiers

PMID40365089
PMCPMC12072972

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.