Evidence map›Paper›PMID 40365064›Full record

ArticleFrontiers in microbiology2025

Screening and transcriptomic analysis of anti-

Ying Wang, Xiaoyan Wu, Xiyuan Fan, Chanxu Han, Fangliang Zheng, Zhenying Zhang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying Wang *Academy of Life Science, Liaoning University, Shenyang, China.
Xiaoyan Wu *Department of Dermatology, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Xiyuan FanAcademy of Life Science, Liaoning University, Shenyang, China.
Chanxu HanDepartment of Dermatology, University of Hong Kong Shenzhen Hospital, Shenzhen, China.
Fangliang ZhengAcademy of Life Science, Liaoning University, Shenyang, China.
Zhenying ZhangDepartment of Dermatology, University of Hong Kong Shenzhen Hospital, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Sporotrichosis is a fungal disease caused by a complex of Methods: Through virtual screening targeting the key gene Results: Azelastine and Mefloquine effectively inhibit S. globosa and S. schenckii. MBC, and MIC for Discussion: Two small-molecule drugs exhibit the ability to inhibit

Indexed as

abaA genesmall molecule drugsSporothrix globosatranscriptomicsvirtual screening

Identifiers

PMID40365064
PMCPMC12069444

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.