Evidence map›Paper›PMID 40365062›Full record

ArticleFrontiers in microbiology2025

Diversity in the composition of pleural cavity and oral cavity microbiota in different bacterial empyema.

Yun Huang, Qing-Hua Gao, Chen-Jian Liu, Ting Su, Jie Liu, Zheng-Yi Liang, Zheng-Ju Zhao, Li-Ping Chen, Yong-Ning Yi, Xiao-Ran Li and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Whole-genome and pan-genome analyses reveal genomic differences among nontypeableFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yun Huang *Faculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Qing-Hua Gao *Faculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Chen-Jian LiuFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Ting SuFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Jie LiuFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Zheng-Yi LiangFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Zheng-Ju ZhaoFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Li-Ping ChenFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Yong-Ning YiFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Xiao-Ran LiFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.
Jian HeFaculty of Life Science and Technology and The Affiliated Anning First People's Hospital, Kunming University of Science and Technology, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recent studies have proposed primary empyema and demonstrated a correlation between it and the microbial composition of the oral cavity. However, no study has systematically characterized the differences in microbial composition between primary and secondary empyema. Furthermore, the correlation between the characteristics of empyema and oral microbiota remains to be explored. Methods: The study included forty-six patients diagnosed with empyema. Hydrothorax was collected from all patients, and mouthwash samples were collected from 24 patients. Both types of samples underwent amplification and sequencing using primer sets specific for the 16S rRNA gene. Results and discussion: Compared with the primary empyema group, the pleural cavity microbial diversity of pneumonia complicated with empyema was significantly decreased (p < 0.05). At the phylum level, the relative abundance of Proteobacteria was significantly higher in the primary empyema group than pneumonia with empyema (p < 0.05). At the genus level, the abundance of

Indexed as

empyemamicrobiotaoral cavitypleural cavitysimilarity

Identifiers

PMID40365062
PMCPMC12069347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.