Evidence map›Paper›PMID 40365019›Full record

ArticleFrontiers in cell and developmental biology2025

Dominant

Cécile Méjécase, Ya Zhou, Nicholas Owen, Pablo Soro-Barrio, Riccardo Cheloni, Neelima Nair, Hajrah Sarkar, Lyes Toualbi, Mariya Moosajee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. USH2A-Mutated Human Retinal Organoids Model Rod-Cone Dystrophy.Investigative ophthalmology & visual science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cécile MéjécaseDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Ya ZhouElectron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Nicholas OwenDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Pablo Soro-BarrioBioinformatics and Biostatistics Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Riccardo CheloniDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Neelima NairDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Hajrah SarkarDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Lyes ToualbiDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.
Mariya MoosajeeDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Retinal dehydrogenase 12 (RDH12) is a photoreceptor NADPH-dependent retinal reductase enzyme, converting all- Methods: As no disease models exist, we generated human induced pluripotent stem cell-derived retinal organoids (RO) from an Results: Discussion: Our study is the first to describe an

Indexed as

autosomal dominantinduced pluripotent stem cellsretinal dehydrogenase 12retinal organoidsretinitis pigmentosavitamin A

Identifiers

PMID40365019
PMCPMC12069300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.