ArticleIndian journal of anaesthesia2025
Effect of perioperative intravenous ketamine on postoperative sleep disturbance in patients undergoing non-cardiac surgery: A systematic review and meta-analysis.
Article in Indian journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Assessment of GRADE utilisation in published systematic review and meta-analysis.Indian journal of anaesthesia · 2026Article
- Automated tools in systematic reviews: Current trends.Indian journal of anaesthesia · 2025Article
- Indian Journal of Anaesthesia Infographics of published articles.Indian journal of anaesthesia · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Postoperative sleep disturbance (PSD) is a common condition that may lead to pain, cognitive impairment, depression, and delayed recovery. This review evaluates the efficacy of perioperative intravenous ketamine in alleviating PSD and offers evidence-based recommendations for clinical practice. Methods: A systematic search was performed in PubMed, Embase, Cochrane Library, Wanfang Data, VIP Information Resource System, China National Knowledge Infrastructure and China Biology Medicine disc (SinoMed) up to 6 Results: A total of 2355 patients from 21 RCTs were analysed. The pooled results indicated that ketamine improved sleep quality compared to placebo on the first postoperative day, as evidenced by a reduction in Pittsburgh Sleep Quality Index scores [mean difference (MD): -2.69; 95% confidence interval (CI): -3.95, -1.42; Conclusion: This meta-analysis indicates that administering ketamine during the perioperative period can enhance postoperative sleep quality. However, the optimal dose, timing and method of administration remain undetermined, emphasising the need for further research to establish standardised guidelines.
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