Evidence map›Paper›PMID 40364800›Full record

ArticleCrohn's & colitis 3602025

US and European Patient and Health Care Professional Perspectives on Fatigue in Ulcerative Colitis and Crohn's Disease: Results From the Communicating Needs and Features of Inflammatory Bowel Disease Experiences Survey.

Remo Panaccione, Alison Potts Bleakman, Stefan Schreiber, Simon Travis, Marla Dubinsky, Toshifumi Hibi, Theresa Hunter Gibble, Tommaso Panni, Cem Kayhan, Eoin J Flynn and 3 more

Abstract read
In one paragraph

Article in Crohn's & colitis 360, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Remo PanaccioneInflammatory Bowel Disease Unit, Division of Gastroenterology and Hepatology, University of Calgary, Calgary, AB, Canada.ORCID https://orcid.org/0000-0002-5247-940X
Alison Potts BleakmanEli Lilly and Company, Indianapolis, IN, USA.
Stefan SchreiberDepartment of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany.
Simon TravisKennedy Institute and Translational Gastroenterology Unit, University of Oxford, Oxford, UK.
Marla DubinskySusan and Leonard Feinstein IBD Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Toshifumi HibiCenter for Advanced IBD Research and Treatment, Kitasato University, Tokyo, Japan.
Theresa Hunter GibbleEli Lilly and Company, Indianapolis, IN, USA.
Tommaso PanniEli Lilly and Company, Indianapolis, IN, USA.
Cem KayhanEli Lilly and Company, Indianapolis, IN, USA.
Eoin J FlynnEli Lilly and Company, Indianapolis, IN, USA.
Angelo D FaviaEli Lilly and Company, Indianapolis, IN, USA.
Christian AtkinsonAdelphi Real World, Bollington, UK.
David T RubinUniversity of Chicago Medicine Inflammatory Bowel Disease Center, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fatigue is a burdensome symptom of Crohn's disease (CD) and ulcerative colitis (UC). The Communicating Needs and Features of Inflammatory Bowel Disease Experiences (CONFIDE) study investigated how patients and health care professionals (HCPs) in the United States (US) and Europe (France, Germany, Italy, Spain, and the United Kingdom) perceived the experiences and impact of CD/UC-related symptoms. Methods: Online, quantitative, cross-sectional surveys were conducted separately among patients with moderate-to-severe CD/UC (defined based on previous treatment, steroid use, and/or hospitalization) and HCPs who treated patients with CD/UC. US and Europe data are presented as descriptive statistics. Results: Surveys were completed by 215 US and 547 European patients with CD, 200 US and 556 European patients with UC, and 200 US and 503 European HCPs. Overall, 35.8% US and 34.2% European patients with CD and 27.5% US and 20.9% European patients with UC reported currently experiencing fatigue (in past month). Most of these patients reported severe fatigue and indicated that CD/UC negatively affected their sleep, energy levels, and quality of life (QoL). The majority of patients currently experiencing but not discussing fatigue with their HCPs at every appointment wished they discussed it more frequently. However, most HCPs reported proactively discussing fatigue at routine appointments. Approximately 20% patients with CD/UC reported declining participation in work/school, social activities, and sports/physical exercise, and avoiding sexual activities due to fatigue. Conclusions: US and European patients with CD/UC experienced severe burden of fatigue, which negatively affected their QoL. Assessing and discussing fatigue in routine appointments is critical for effectively managing this debilitating symptom.

Indexed as

Crohn’s diseasefatiguequality of lifeulcerative colitis

Identifiers

PMID40364800
PMCPMC12070485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.