ArticleCurrent medical imaging2025
Cavum Septi Pellucidi et Vergae in the Pathogenesis of Prenatally Detected Ventriculomegaly.
Article in Current medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThe main objective of this work was to investigate the effect of cavum septi pellucidi et vergae (CSPV) on the pathogenesis of ventriculomegaly (VM) cases detected during the fetal period. MATERIALS AND
methodsThe fetuses of 515 mothers who applied to the Department of Radiology between October 2011 and December 2022 and who had undergone fetal magnetic resonance imaging (fMRI) were evaluated retrospectively. 152 fetuses with CSPV were included in the study. The fetuses were separated into the following groups: those with right VM (n = 20), those with left VM (n = 56), and those with bilateral VM (n = 44). Fetuses with CSPV, but without VM (n = 32), were included in the study as the control group. For the group with CSPV, lines were drawn to divide the fetal cranium into two symmetrical parts at the interhemispheric line in the axial and coronal planes. The distances from these lines to the lateral leaves of the CSPV were measured. In addition, measurements of the CSPV (anteroposterior, transverse, and high) were taken. An evaluation of whether that was associated with ventricular width or maternal age and gestational week was conducted.
resultsThe left ventricular width was significantly higher in cases where the CSPV deviated more to the right, and the right ventricular width was significantly higher in cases where the CSPV deviated more to the left. When the VM rates in the VM group without CSPV and the VM rates in the VM group with CSPV were compared, the VM rates were found to be significantly higher in those with CSPV.
conclusionFetuses with CSPV should be followed up for the possibility of developing VM. However, it should be remembered that VM may be a variation due to CSPV. There is an inverse relationship between the side where CSPV deviates and the side where VM is observed.
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