Evidence map›Paper›PMID 40364476›Full record

ArticleActa dermato-venereologica2025

Identifying Mild-to-Moderate Atopic Dermatitis Using a Generic Machine Learning Approach: A Danish National Health Register Study.

Mie Sylow Liljendahl, Kristina Ibler, Christian Vestergaard, Lone Skov, Pavika Jain, Jan Håkon Rudolfsen, Ann Hærskjold, Mathias Torpet

Abstract read
In one paragraph

Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Atopic Dermatitis in Denmark: Regional Variation.Acta dermato-venereologica · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mie Sylow LiljendahlDepartment of Dermatology and Allergy, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark.
Kristina IblerDepartment of Dermatology, Bispebjerg Hospital, Copenhagen University Hospital, Denmark.
Christian VestergaardDepartment of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
Lone SkovDepartment of Dermatology and Allergy, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Pavika JainMarket Access, Sanofi Denmark A/S.
Jan Håkon RudolfsenEY, Frederiksberg, Denmark. Janhrudolfsen@gmail.com.
Ann HærskjoldDepartment of Dermatology, Bispebjerg Hospital, Copenhagen University Hospital, Denmark.
Mathias TorpetMedical Affairs, Sanofi Denmark A/S.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atopic dermatitis is a chronic skin disease, causing itching and recurrent eczematous lesions. In Danish national register data, adults with atopic dermatitis can only be identified if they have a hospital-diagnosed atopic dermatitis. The purpose of this study was to develop a machine learning model to identify all patients with atopic dermatitis by proxy, using data for contacts with primary care, prescription medication, and hospital contacts not related to skin diseases. Individuals redeeming a prescription for dermatological preparations were extracted as potential patients with atopic dermatitis. Individuals with a registered hospital diagnosis of atopic dermatitis were classified as "Known AD", "Other skin disease" (registrations of other dermatological diagnosis codes indicating other skin disease), or "Uncertain AD status"' (no hospital diagnosis registered). Patients categorized as "Known AD" and "Other skin disease" were used to develop the model. All uses of healthcare services 2 years prior to hospital diagnosis were used as potential predictors. The data were split into training and validation sets (70/30). From 1996 to 2022, 385,135 individuals had uncertain atopic dermatitis status. The most important predictors were corticosteroid prescriptions for dermatological use, consultations with dermatologist, and age. Of the 385,135 individuals, the model predicted that 230,522 individuals likely have atopic dermatitis.

Indexed as

Dermatitis, AtopicMachine LearningAdolescentAdultAgedDenmarkFemaleHumansMaleMiddle AgedPredictive Value of TestsRegistriesSeverity of Illness IndexYoung Adult

Identifiers

PMID40364476
PMCPMC12103080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.