Evidence map›Paper›PMID 40364419›Full record

ReviewPlants (Basel, Switzerland)2025

Medicinal Plants Against Dental Caries: Research and Application of Their Antibacterial Properties.

Marcela Alejandra Gloria-Garza, Gustavo Raúl Reyna-Martínez, Zacarías Jiménez-Salas, Eduardo Campos-Góngora, Miroslava Kačániová, Diana Elena Aguirre-Cavazos, Minerva Bautista-Villarreal, Catalina Leos-Rivas, Joel Horacio Elizondo-Luevano

Abstract readReview
In one paragraph

Review in Plants (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Targeting Oral Pathogens withAntibiotics (Basel, Switzerland) · 2025
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Marcela Alejandra Gloria-GarzaFacultad de Odontología, Universidad Autónoma de Nuevo León, Dr. Eduardo Aguirre Pequeño S/N, Monterrey 64460, NL, Mexico.ORCID 0000-0002-2838-3774
Gustavo Raúl Reyna-MartínezFacultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.ORCID 0000-0001-6909-6459
Zacarías Jiménez-SalasFacultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León, Dr. Eduardo Aguirre Pequeño S/N, Monterrey 64460, NL, Mexico.ORCID 0000-0002-1544-0899
Eduardo Campos-GóngoraFacultad de Salud Pública y Nutrición, Universidad Autónoma de Nuevo León, Dr. Eduardo Aguirre Pequeño S/N, Monterrey 64460, NL, Mexico.
Miroslava KačániováInstitute of Horticulture, Faculty of Horticulture and Landscape Engineering, Slovak University of Agriculture, Tr. A. Hlinku 2, 94976 Nitra, Slovakia.ORCID 0000-0002-4460-0222
Diana Elena Aguirre-CavazosFacultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.
Minerva Bautista-VillarrealFacultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.ORCID 0000-0001-7975-1488
Catalina Leos-RivasFacultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.
Joel Horacio Elizondo-LuevanoFacultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, Av. Universidad S/N, Cd. Universitaria, San Nicolás de los Garza 66455, NL, Mexico.ORCID 0000-0003-2954-5939

Funding

Consejo Nacional de Humanidades, Ciencias y Tecnologías CVU: 242099, 350961, 73541, 120718, 486943, and 418935Consejo Nacional de Humanidades, Ciencias y Tecnologías I1200/320/2022Consejo Nacional de Humanidades, Ciencias y Tecnologías I1200/331/2023Slovak Research and Development Agency APVV-20-0058 "The potential of the essential oils from aromatic plants for medical use and food preservation"
6 · The paper itself

Abstract

Dental caries remains one of the most widespread global health concerns, significantly affecting both oral and overall health. Conventional treatments typically rely on chemical-based products which, although effective, are often associated with undesirable side effects such as tooth staining, altered taste, and the development of antimicrobial resistance. As a response, plant-based natural alternatives have gained attention as promising strategies for the prevention and management of dental caries. This review highlights the antibacterial properties of medicinal plants and their potential applications in dentistry, with a particular focus on their activity against a broad range of bacteria and microorganisms involved in oral diseases. Numerous plant extracts and bioactive compounds-including polyphenols, flavonoids, and essential oils-have demonstrated antimicrobial, anti-inflammatory, and antioxidant properties that contribute to maintaining oral health. Although in vitro and in vivo studies support their therapeutic potential, clinical trials assessing long-term efficacy and safety remain scarce. Future research should prioritize the standardization of extraction methods, dosage, and formulations to facilitate the integration of these natural alternatives into conventional dental care practices.

Indexed as

bacteriacariesethnopharmacologyextractsmedicinal plantsnatural productsplant therapiespreventive dentistry

Identifiers

PMID40364419
PMCPMC12073129

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.