Evidence map›Paper›PMID 40364243›Full record

ReviewJournal of clinical medicine2025

Cardiac Resynchronization Therapy and Conduction System Pacing.

Thomas Garvey O'Neill, Takahiro Tsushima, Bhupendar Tayal

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Thomas Garvey O'NeillDepartment of Medicine, University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Takahiro TsushimaDepartment of Medicine, Division of Cardiology, University Hospitals Harrington Heart & Vascular Institute, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.ORCID 0000-0003-0190-7555
Bhupendar TayalDepartment of Medicine, Division of Cardiology, University of Arkansas Medical Center, Little Rock, AR 72205, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Left bundle branch block (LBBB), initially described in the early 20th century, has become increasingly recognized as one of the leading causes of advanced heart failure (HF). In addition to rapidly growing data on guideline-directed medical therapy, cardiac resynchronization therapy (CRT) via transvenous coronary sinus lead has been the gold-standard therapy, but one-third of the indicated patients do not receive the expected benefits. Recently, cardiac conduction system pacing (CSP) was identified as an alternative to traditional CRT strategy, and multiple data have been published during the last few years. This review will discuss the diagnostic criteria of LBBB and its relation to the development of HF and review available data for traditional CRT as well as CSP in depth.

Indexed as

cardiac resynchronization therapyconduction system pacingleft bundle branch block

Identifiers

PMID40364243
PMCPMC12072991

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.