Synthesis and Biological Screening of Structurally Modified Phaeosphaeride Analogues.

Konstantinos Rantzios, Oraia-Eirini Chatzimentor, George Leonidis, Jorgo Giuliani, Ioanna Sigala, Vasiliki Sarli

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in

0citing papers in PubMed

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Konstantinos RantziosDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.

Oraia-Eirini ChatzimentorDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.

George LeonidisDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0002-3286-4781

Jorgo GiulianiDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.

Ioanna SigalaDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0002-8604-9870

Vasiliki SarliDepartment of Chemistry, Aristotle University of Thessaloniki, University Campus, 54124 Thessaloniki, Greece.ORCID 0000-0002-6128-8277

Funding

NSRF 2014-2020 MIS5002691

6 · The paper itself

Abstract

Phaeosphaeride A and its analogues have been extensively explored for their potential pharmacological applications, particularly in the development of anticancer agents. In this study, the synthesis of structurally modified phaeosphaeride analogues is reported. The structures of the synthesized analogues bearing the tetrahydro- and hexahydro-2

Indexed as

Antineoplastic AgentsCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansMolecular StructureStructure-Activity RelationshipAntineoplastic Agentsanticancernatural product analoguesphaeosphaeridetetramatetetronate

Identifiers

PMID40363821

DOI10.3390/molecules30092016

PMCPMC12073321

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