Evidence map›Paper›PMID 40363646›Full record

ArticleMaterials (Basel, Switzerland)2025

Effect of Ti6Al4V Alloy Surface and Porosity on Bone Osseointegration: In Vivo Pilot Study in Rabbits.

Amparo Vanaclocha, Vicente Vanaclocha, Carlos M Atienza, Pablo Jordá-Gómez, Víctor Primo-Capella, Jose R Blasco, Luis Portolés, Nieves Saiz-Sapena, Leyre Vanaclocha

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Amparo VanaclochaBiomechanics Institute of Valencia, Polytechnic University of Valencia, 46022 Valencia, Spain.
Vicente VanaclochaDepartment of Surgery, Division of Neurosurgery, University of Valencia, 46010 Valencia, Spain.ORCID 0000-0002-4909-5886
Carlos M AtienzaBiomechanics Institute of Valencia, Polytechnic University of Valencia, 46022 Valencia, Spain.
Pablo Jordá-GómezHospital General Universitario de Castellón, 12004 Castellón de la Plana, Spain.ORCID 0000-0003-0160-4431
Víctor Primo-CapellaBiomechanics Institute of Valencia, Polytechnic University of Valencia, 46022 Valencia, Spain.ORCID 0000-0002-2561-5795
Jose R BlascoAIDIMME-Metal Processing, Furniture, Wood and Packaging Technology Institute, Parque Tecnológico, Avda. Leonardo Da Vinci 38, 46980 Paterna, Spain.
Luis PortolésAIDIMME-Metal Processing, Furniture, Wood and Packaging Technology Institute, Parque Tecnológico, Avda. Leonardo Da Vinci 38, 46980 Paterna, Spain.
Nieves Saiz-SapenaHospital General Universitario de Valencia, 46014 Valencia, Spain.ORCID 0000-0001-7816-3617
Leyre VanaclochaMedius Klinik, Ostfildern-Ruit Klinik für Urologie, Hedelfinger Strasse 166, 73760 Ostfildern, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unmodified Ti6Al4V can osseointegrate, but sometimes this capacity needs to be improved. This study aimed to see how much porosity improves osseointegration in a Ti6Al4V implant. Three types of Ti6Al4V cylindrical-shaped implants (13.00 mm length × 5.00 mm diameter) were evaluated: solid sandblasted acid-etched, sintered, and porous 3D-printed (681.00 µm average pore size). Fifteen 20-week-old nullipara female parasite-free New Zealand California white rabbits were used, employing the femoral condyle defect model and undertaking µ-CT analysis and pull-out testing eight weeks later. On µ-CT densitometric analysis, the solid sandblasted rod showed the highest new bone growth around the implant. Bone growth was higher inside the implants for the porous 3D-printed (54.00 ± 5.00 mm

Indexed as

bone–implant interactionsbone–implant interfaceimplant surface designosseointegrationporous implantstitanium implants

Identifiers

PMID40363646
PMCPMC12072787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.