Evidence map›Paper›PMID 40363631›Full record

ArticleMaterials (Basel, Switzerland)2025

Biosafety and Blood Compatibility of Graphene Oxide Particles in In Vitro Experiments.

Yuriy Prylutskyy, Patrycja Bełdzińska, Natalia Derewońko, Tetiana Halenova, Nataliia Raksha, Marcin Zakrzewski, Grzegorz Gołuński, Svitlana Prylutska, Uwe Ritter, Olexii Savchuk and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuriy PrylutskyyESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Patrycja BełdzińskaLaboratory of Biophysics, University of Gdańsk, 80-307 Gdańsk, Poland.
Natalia DerewońkoLaboratory of Recombinant Vaccines, University of Gdańsk, 80-307 Gdańsk, Poland.
Tetiana HalenovaESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.ORCID 0000-0003-2973-2646
Nataliia RakshaESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.
Marcin ZakrzewskiLaboratory of Biophysics, University of Gdańsk, 80-307 Gdańsk, Poland.ORCID 0000-0003-4920-7996
Grzegorz GołuńskiLaboratory of Biophysics, University of Gdańsk, 80-307 Gdańsk, Poland.
Svitlana PrylutskaFaculty of Plant Protection, Biotechnology and Ecology, National University of Life and Environmental Science of Ukraine, 03041 Kyiv, Ukraine.
Uwe RitterInstitute of Chemistry and Biotechnology, Technical University of Ilmenau, 98693 Ilmenau, Germany.ORCID 0000-0002-9315-4863
Olexii SavchukESC "Institute of Biology and Medicine", Taras Shevchenko National University of Kyiv, 01601 Kyiv, Ukraine.ORCID 0000-0003-3621-6981
Jacek PiosikLaboratory of Biophysics, University of Gdańsk, 80-307 Gdańsk, Poland.ORCID 0000-0002-5671-1915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graphene oxide (GO), owing to its extraordinary application prospects in biomedicine, is attracting growing research attention. However, the biosafety and blood compatibility of GO required for its clearance for use in clinical trials remain elusive. Therefore, we studied the mutagenic properties of GO as well as its cell toxicity and blood compatibility. Prior to biological experiments, we assessed the structural organization of GO using dynamic light scattering and microscopic visualization methods. The results of both the Ames mutagenicity test performed on

Indexed as

AlamarBlue cytotoxicity testAmes mutagenicity testatomic force microscopyblood compatibilitydynamic light scatteringhemolytic assayrabbit plasma coagulationrabbit platelet aggregationSalmonella enterica serovar Typhimurium

Identifiers

PMID40363631
PMCPMC12072977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.