Evidence map›Paper›PMID 40363113›Full record

ReviewSensors (Basel, Switzerland)2025

Fluorometric and Colorimetric Biosensors for the Assay of Cholinesterase Inhibitors.

Miroslav Pohanka

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A molecular probe for detecting cholinesterase activity in MRI.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Miroslav PohankaMilitary Faculty of Medicine, University of Defense, Trebesska 1575, 500 02 Hradec Kralove, Czech Republic.ORCID 0000-0001-8804-8356

Funding

Ministry of Defence DZRO-FVZ22-ZHN II
6 · The paper itself

Abstract

Cholinesterases, specifically acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), play critical roles in neurotransmission and are key targets for inhibitors with therapeutic and toxicological significance. This review focuses on the development and application of fluorometric and colorimetric biosensors for the detection of cholinesterase inhibitors. These biosensors take advantage of the unique properties of AChE and BChE to provide sensitive and selective detection methods essential for environmental monitoring, food safety, and clinical diagnostics. Recent advances in assay techniques, including the use of gold nanoparticles, pseudoperoxidase nanomaterials, and innovative enzyme-substrate interactions, are highlighted. This review also discusses challenges and future directions for optimizing these biosensors for practical applications, emphasizing their potential to enhance public health and safety.

Indexed as

Biosensing TechniquesCholinesterase InhibitorsColorimetryFluorometryAcetylcholinesteraseButyrylcholinesteraseGoldHumansMetal NanoparticlesAcetylcholinesteraseButyrylcholinesteraseCholinesterase InhibitorsGoldacetylcholinesteraseassaybutyrylcholinesteraseenzymegold nanoparticlesnerve agentsneurotoxinperoxidasephotogrammetry

Identifiers

PMID40363113
PMCPMC12074314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.