Evidence map›Paper›PMID 40362804›Full record

ArticleNutrients2025

Dietary Rutin Ameliorates Nanoparticle Zinc Oxide-Induced Toxicity in Mice by Potentiating Antioxidant Defense Mechanisms.

Xiaofang He, Longfei Ma, Jiaqi Zhang, Binbin Zhou, Shun Chen, Minhang Tu, Gentan Cai, Tian Wang, Chao Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaofang HeCollege of Animal Science and Food Engineering, Jinling Institute of Science and Technology, Nanjing 211169, China.ORCID 0009-0004-9635-5144
Longfei MaCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Jiaqi ZhangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Binbin ZhouCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.ORCID 0000-0002-4562-4998
Shun ChenCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Minhang TuCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Gentan CaiCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Tian WangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Chao WangCollege of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.

Funding

High level talents start the project of JIT JIT-B-202036Industry-university-research Project of Jiangsu Province BY2022605National Natural Science Foundation of China No.31972598
6 · The paper itself

Abstract

In animal production, nanoparticulate zinc oxide exhibits synergistic antibacterial efficacy coupled with growth-promoting effects, positioning itself as a novel antibiotic alternative with enhanced biosafety profiles. However, its dose-dependent toxicity poses challenges.

Indexed as

AntioxidantsMetal NanoparticlesNanoparticlesRutinZinc OxideAnimalsApoptosisDietary SupplementsKidneyLiverMaleMiceNF-E2-Related Factor 2Oxidative StressZincAntioxidantsNF-E2-Related Factor 2RutinZincZinc Oxideantioxidant capacityhepatic functionmitochondrial dysfunctionrutinzinc oxide nanoparticle

Identifiers

PMID40362804
PMCPMC12073253

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.