Evidence map›Paper›PMID 40362799›Full record

Trial reportNutrients2025

Clinical Efficacy of Probiotics for Relieving Cold Symptoms in Healthy Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.

Lisa Lungaro, Patrizia Malfa, Francesca Manza, Matilde Negrelli, Anna Costanzini, Diletta Francesca Squarzanti, Marta Lo Re, Alessio Cariani, Sara Ghisellini, Fabio Caputo and 5 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Probiotic Modulation in Aging: Strain-Specific Geroprotective Effects inInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lisa LungaroDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-9053-5671
Patrizia MalfaSynBalance srl, 21040 Origgio, Italy.ORCID 0009-0001-1327-5682
Francesca ManzaDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-2898-4323
Matilde NegrelliDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0009-0005-7133-8433
Anna CostanziniDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-8644-1135
Diletta Francesca SquarzantiSynBalance srl, 21040 Origgio, Italy.ORCID 0000-0001-8090-7718
Marta Lo ReSynBalance srl, 21040 Origgio, Italy.
Alessio CarianiClinical Pathology Unit, S. Anna University Hospital, 44124 Ferrara, Italy.
Sara GhiselliniClinical Pathology Unit, S. Anna University Hospital, 44124 Ferrara, Italy.ORCID 0009-0007-3194-9621
Fabio CaputoDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-8953-8338
Alfredo De GiorgiDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.
Pasquale MansuetoGeriatric Unit, P. Giaccone University Hospital, 90127 Palermo, Italy.ORCID 0000-0002-0406-0583
Antonio CarroccioUnit of Internal Medicine, "V. Cervello" Hospital, Ospedali Riuniti "Villa Sofia-Cervello", 90146 Palermo, Italy.ORCID 0000-0001-8913-7916
Roberto De GiorgioDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0003-0867-5873
Giacomo CaioDepartment of Translational Medicine, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0002-4244-4529

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Common ColdProbioticsAdolescentAdultCytokinesDietary SupplementsDouble-Blind MethodFemaleHealthy VolunteersHumansMaleMyalgiaQuality of LifeTreatment OutcomeYoung AdultCytokinescold symptomsfood supplementsimmunityprobioticsURTIs

Identifiers

PMID40362799
PMCPMC12073269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.