Evidence map›Paper›PMID 40362743›Full record

ArticleNutrients2025

Association Between the Dietary Inflammatory Index and Depression in Mid-Pregnancy: Mediating Effect of Sleep Quality.

Zhitan Zhang, Cong Huang, Hua Zhang, Xun Huang, Zixin Zhong, Fan Xia, Junwei He, Yuxin Ma, Chang Liu, Hongzhuan Tan and 3 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zhitan ZhangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Cong HuangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Hua ZhangQingdao Huangdao District Market Supervision Administration, No. 627 Binhai Avenue, Qingdao West Coast New District, Qingdao 266427, China.
Xun HuangDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Zixin ZhongDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Fan XiaDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Junwei HeDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Yuxin MaDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Chang LiuDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Hongzhuan TanDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Jing DengDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.ORCID 0000-0002-7801-4379
Mengshi ChenDepartment of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.
Xianyang LeiDepartment of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, No. 172 Tongzipo Road, Yuelu District, Changsha 410013, China.ORCID 0009-0005-4501-8436

Funding

the Natural Science Foundation of Hunan Province,China No. 2024JJ9043
6 · The paper itself

Abstract

objectiveThe aim of this study was to assess the association between the Dietary Inflammatory Index (DII) and depression in mid-pregnancy and the mediating effect of sleep quality according to the Edinburgh Postnatal Depression Scale (EPDS).

methodsThis was a cross-sectional study conducted in 2017-2019 at a maternal and child health centre in Hunan Province. After applying the inclusion and exclusion criteria, 749 pregnant women were finally included in this study. A multifactorial logistic regression model was used to estimate the odds ratio (OR) and 95% confidence interval (95% CI) of the mid-pregnancy DII on mid-pregnancy depression. Restricted cubic spline plot regression was used to analyse the nonlinearity of the association between DII and depression. Mediation effects models were used to analyse the mediating role of sleep quality.

resultsThe average age of the 749 pregnant women was 29.42 ± 4.22 years. The mean mid-pregnancy DII was 0.21 ± 1.48 and the overall presenting rate of mid-pregnancy depression was 9.35%. In the final model adjusted for covariates such as maternal age, race, mid-pregnancy body mass index (BMI), occupation, literacy, and mean monthly income, the risk of depression in mid-pregnancy DII Q3 was 3.51 times higher than the mid-pregnancy DII Q4 [OR = 3.51, 95% CI = (1.45 to 8.53)]. A high DII in mid-pregnancy was a risk factor for depression in mid-pregnancy (

conclusionsA high DII is a risk factor for mid-pregnancy depression. The Dietary Inflammatory Index can influence depression not only directly but also indirectly through the mediating effect of sleep quality on mid-pregnancy depression.

Indexed as

DepressionDietInflammationPregnancy ComplicationsSleep QualityAdultBody Mass IndexChinaCross-Sectional StudiesFemaleHumansPregnancyRisk FactorsYoung Adultdepressiondiet/adverse effectsinflammationpregnancysleep quality

Identifiers

PMID40362743
PMCPMC12073339

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.