Evidence map›Paper›PMID 40362714›Full record

ArticleNutrients2025

The Combined Effect of High-Intensity Interval Training and Time-Restricted Feeding on the AKT-IGF-1-mTOR Signaling Pathway in the Muscle Tissue of Type 2 Diabetic Rats.

Motahareh Mohebinejad, Fatemeh Kazeminasab, Mahtab Ghanbari Rad, Reza Bagheri, Mazdak Razi, Darryn Willoughby, Fred Dutheil

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Motahareh MohebinejadDepartment of Physical Education and Sports Science, Faculty of Humanities, University of Kashan, Kashan 87317-53153, Iran.
Fatemeh KazeminasabDepartment of Physical Education and Sports Science, Faculty of Humanities, University of Kashan, Kashan 87317-53153, Iran.ORCID 0000-0002-7309-3637
Mahtab Ghanbari RadGerash Cellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash 58666-74417, Iran.
Reza BagheriDepartment of Exercise Physiology, University of Isfahan, Isfahan 81746-73441, Iran.ORCID 0000-0003-1433-2906
Mazdak RaziDivision of Comparative Histology and Embryology, Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia 57561-51818, Iran.
Darryn WilloughbyDepartment of Education, Innovation, and Technology, Baylor College of Medicine-School of Medicine, Temple, TX 76513, USA.ORCID 0000-0001-9810-602X
Fred DutheilPreventive and Occupational Medicine, Université Clermont Auvergne, CNRS, LaPSCo, Physiological and Psychosocial Stress, CHU Clermont-Ferrand, University Hospital of Clermont-Ferrand, Witty Fit, F-63000 Clermont-Ferrand, France.ORCID 0000-0002-1468-6029

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2High-Intensity Interval TrainingInsulin-Like Growth Factor IMuscle, SkeletalPhysical Conditioning, AnimalProto-Oncogene Proteins c-aktTOR Serine-Threonine KinasesAnimalsBlood GlucoseDiet, High-FatInsulin ResistanceMaleRatsRats, WistarSignal TransductionBlood Glucoseinsulin-like growth factor-1, ratInsulin-Like Growth Factor ImTOR protein, ratProto-Oncogene Proteins c-aktTOR Serine-Threonine Kinasesdiabeteshigh-fat diethigh-intensity interval traininginsulin resistanceintermittent fasting

Identifiers

PMID40362714
PMCPMC12073226

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.